Department of Cardiothoracic and Vascular Surgery, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Department of Radiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
J Thorac Cardiovasc Surg. 2015 Oct;150(4):880-8. doi: 10.1016/j.jtcvs.2015.07.027. Epub 2015 Jul 15.
This study investigates whether the no-touch (NT) vein graft, at a mean time of 16 years, maintains a significantly higher patency rate than conventional (C) vein grafts and still has patency comparable to that of the left internal thoracic artery (LITA).
A total of 156 patients accepted for coronary artery bypass grafting were randomly allocated to 1 of 3 groups. In the C group, the saphenous vein (SV) was stripped and distended. In the intermediate group, the SV was stripped but not distended. In the NT group, the SV was neither stripped nor distended, but rather harvested with a fat pedicle. This study is an angiographic follow-up of the C and NT groups, at a mean time of 16 years postoperatively.
Fifty-four patients were included (C group = 27; NT group = 27). In all, 72 and 75 vein grafts were completed in groups C and NT, respectively. Crude SV graft patency was 64% in the C group versus 83% in the NT group (P = .03), which was similar to the patency of the LITA (88%). The harvesting technique had a major impact on the patency with a hazard ratio for occlusion of 1.83 for the C group (P = .04).
Harvesting the SV with the NT technique conferred, at a mean time of 16 years, a significantly higher patency than the conventional technique that was still comparable to that of the LITA.
本研究旨在探讨在 16 年的时间里,非接触(NT)静脉移植物是否比传统(C)静脉移植物保持更高的通畅率,并且仍然具有与左内乳动脉(LITA)相当的通畅率。
共有 156 名接受冠状动脉旁路移植术的患者被随机分配到 3 组中的 1 组。在 C 组中,剥脱并扩张隐静脉(SV)。在中间组中,SV 被剥脱但未扩张。在 NT 组中,SV 既未被剥脱也未被扩张,而是带有脂肪蒂进行采集。本研究是对 C 组和 NT 组术后 16 年的血管造影随访。
共纳入 54 例患者(C 组=27 例;NT 组=27 例)。在 C 组和 NT 组中,分别完成了 72 个和 75 个静脉移植物。C 组的 SV 移植物通畅率为 64%,NT 组为 83%(P=.03),与 LITA 的通畅率(88%)相似。采集技术对通畅率有重大影响,C 组的闭塞风险比为 1.83(P=.04)。
在 16 年的时间里,采用 NT 技术采集 SV 的通畅率明显高于传统技术,与 LITA 的通畅率相当。