Bajwa Sukhminder Jit Singh, Haldar Rudrashish
Department of Anaesthesiology and Intensive Care, Gian Sagar Medical College and Hospital, Banur, Punjab, India.
Department of Anaesthesiology, SGPGIMS, Lucknow, Uttar Pradesh, India.
J Craniovertebr Junction Spine. 2015 Jul-Sep;6(3):105-10. doi: 10.4103/0974-8237.161589.
Spinal procedures are generally associated with intense pain in the postoperative period, especially for the initial few days. Adequate pain management in this period has been seen to correlate well with improved functional outcome, early ambulation, early discharge, and preventing the development of chronic pain. A diverse array of pharmacological options exists for the effective amelioration of post spinal surgery pain. Each of these drugs possesses inherent advantages and disadvantages which restricts their universal applicability. Therefore, combination therapy or multimodal analgesia for proper control of pain appears as the best approach in this regard. The current manuscript discussed the pathophysiology of postsurgical pain including its nature, the various tools for assessment, and the various pharmacological agents (both conventional and upcoming) available at our disposal to respond to post spinal surgery pain.
脊柱手术通常在术后会伴有剧痛,尤其是在最初的几天。在此期间进行充分的疼痛管理已被证明与改善功能预后、早期活动、早期出院以及预防慢性疼痛的发生密切相关。有多种药理学选择可有效缓解脊柱手术后的疼痛。这些药物每种都有其固有的优缺点,这限制了它们的普遍适用性。因此,联合治疗或多模式镇痛以适当控制疼痛似乎是这方面的最佳方法。本手稿讨论了术后疼痛的病理生理学,包括其性质、各种评估工具以及我们可用于应对脊柱手术后疼痛的各种药理学药物(包括传统药物和新出现的药物)。