不伴有炎症性肠病的巨大丝状息肉病：一例报告
Giant Filiform Polyposis not Associated with Inflammatory Bowel Disease: A Case Report.
作者信息
Ponte Rossella, Mastracci Luca, Di Domenico Stefano, Ferretti Carlotta, De Cian Franco, Fiocca Roberto, Grillo Federica
机构信息
Pathology Unit, Department of Surgical Science and Integrated Diagnostics, University of Genoa, Genoa, Italy.
Pathology Unit, Department of Surgical Science and Integrated Diagnostics, University of Genoa, Genoa, Italy ; IRCCS AOU San Martino IST, Genoa, Italy.
出版信息
Viszeralmedizin. 2015 Feb;31(1):58-60. doi: 10.1159/000370342.
BACKGROUND
Filiform polyposis (FP) is an uncommon cause of non-neoplastic and non-syndromic polyposis. Several hypotheses concerning its pathogenesis have been published. FP is most frequently associated with a post-inflammatory reparative process; indeed, the most frequent association is with inflammatory bowel disease (IBD). FP is characterized by one to hundreds of uniform, slender, arborizing, vermiform projections of the large bowel mucosa and submucosa lined by normal or inflamed colonic mucosa. The most common sites for these polyps are the transverse and descending colon.
CASE REPORT
In this report we present a case of giant FP associated with locally invasive adenocarcinoma of the right colon in a 73-year-old man with no past medical history of IBD.
CONCLUSION
Few of these cases have been reported in the literature, and out of the approximately 20 of such case reports only one other was associated with colorectal adenocarcinoma.
背景
丝状息肉病（FP）是一种非肿瘤性、非综合征性息肉病的罕见病因。关于其发病机制的几种假说已发表。FP最常与炎症后修复过程相关；实际上，最常见的关联是与炎症性肠病（IBD）。FP的特征是大肠黏膜和黏膜下层有一到数百个均匀、细长、分支状、蠕虫状的突起，内衬正常或发炎的结肠黏膜。这些息肉最常见的部位是横结肠和降结肠。
病例报告
在本报告中，我们呈现了一例73岁男性的巨大FP病例，该患者既往无IBD病史，同时伴有右半结肠癌局部浸润性腺癌。
结论
文献中报道的此类病例很少，在大约20篇此类病例报告中，只有另一例与结直肠腺癌相关。
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