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[表皮葡萄球菌在新生儿败血症病因学中的作用]

[Role of Staphylococcus epidermidis in the etiology of septicemia in newborn infants].

作者信息

Galczak W, Mikołajczyk W

出版信息

Pediatr Pol. 1989 May;64(5):304-9.

PMID:2628897
Abstract

124 newborns admitted to the Department within the period of 3 years with suspected sepsis were analysed. In 55.6% of children, boys prevailing (62.3%), generalized infection was confirmed with positive bacterial cultures. Late-onset disease predominance was found (72.8%). The mortality rate in this group was 5.8% (11.3% boys and 1.9% girls). Analysis of the causative organisms revealed more frequently the Gram positive bacteria (81% of all positive cultures) with a predominant role of Staphylococcus epidermidis (43.5%). The pathogenic role of Staphylococcus epidermidis (regarded by some other authors as a contamination) was stressed. Its increasing clinical significance has been correlated with a deterioration of sanitary and hygienic conditions at the obstetric and neonatal wards, wider application of invasive procedures and antibiotics.

摘要

对3年内收治入该科室的124例疑似败血症新生儿进行了分析。在55.6%的儿童中,男孩占多数(62.3%),细菌培养阳性确诊为全身性感染。发现晚发型疾病占优势(72.8%)。该组的死亡率为5.8%(男孩为11.3%,女孩为1.9%)。对致病菌的分析显示,革兰氏阳性菌更为常见(在所有阳性培养物中占81%),其中表皮葡萄球菌起主要作用(43.5%)。强调了表皮葡萄球菌的致病作用(其他一些作者认为是污染)。其临床意义的增加与产科和新生儿病房卫生条件的恶化、侵入性操作和抗生素的广泛应用有关。

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