Gastroenterology Department, Georges Pompidou European Hospital, Paris, France; Paris Descartes University, Paris, France.
Gastroenterology Department, Georges Pompidou European Hospital, Paris, France; Paris Descartes University, Paris, France.
Am J Med. 2015 Dec;128(12):1363.e1-8. doi: 10.1016/j.amjmed.2015.07.029. Epub 2015 Aug 17.
Chronic mesenteric ischemia is a rare disease with nonspecific clinical symptoms, such as chronic postprandial abdominal pain and weight loss. Diagnostic modalities and revascularization techniques have evolved during the past 20 years. The significance of stenosis in a single splanchnic vessel remains unclear. Our aims were to assess the outcomes of 2 revascularization techniques and report on the diagnostic modalities of splanchnic vessel stenoses.
The demographic data, medical history, technical characteristics, and outcomes of the revascularization procedures were recorded for all of the patients admitted for endovascular revascularization or open surgical revascularization of the splanchnic vessels as treatment for chronic mesenteric ischemia in our tertiary referral center since 2000.
Fifty-four patients were included in this study: 43 received endovascular revascularization, and 11 had open surgical revascularization. The symptoms were abdominal pain, weight loss, and diarrhea in 98%, 53%, and 25% of the cases, respectively. Computed tomography angiography was the key diagnostic tool for 60% of the patients. A single-vessel stenosis was found in one-third of the patients. Endovascular and open revascularization had similar early and late outcomes, and no 30-day mortality was observed. However, we did observe higher morbidity in the open revascularization group (73% vs 19%, P <.03).
Chronic mesenteric ischemia may be diagnosed in the presence of a splanchnic syndrome and stenosis of a single splanchnic vessel, typically assessed using computed tomography angiography. In selected patients, endovascular revascularization had similar efficacy as, and lower complication rates than open revascularization.
慢性肠系膜缺血是一种罕见疾病,其临床症状不具有特异性,如慢性餐后腹痛和体重减轻。在过去的 20 年中,诊断方法和血运重建技术不断发展。单一内脏血管狭窄的意义尚不清楚。我们的目的是评估两种血运重建技术的结果,并报告内脏血管狭窄的诊断方法。
记录了 2000 年以来在我们的三级转诊中心因慢性肠系膜缺血接受内脏血管腔内或开放手术血运重建治疗的所有患者的人口统计学数据、病史、技术特征和血运重建结果。
本研究共纳入 54 例患者:43 例行腔内血管重建,11 例行开放手术血管重建。98%、53%和 25%的患者分别表现为腹痛、体重减轻和腹泻。60%的患者的主要诊断工具为 CT 血管造影。三分之一的患者存在单支血管狭窄。腔内和开放血运重建的早期和晚期结果相似,无 30 天死亡率。然而,我们确实观察到开放血运重建组的发病率更高(73%比 19%,P <.03)。
存在内脏综合征和单一内脏血管狭窄时可能诊断为慢性肠系膜缺血,通常使用 CT 血管造影评估。在选择的患者中,腔内血管重建的疗效与开放血管重建相似,并发症发生率较低。