Raimer-Hall Dawn, Shea Heidi Chamberlain
Pediatr Nurs. 2015 Mar-Apr;41(2):72-7.
Self-injection of growth hormone (GH) by children with GH deficiency can be problematic. They may have difficulty manipulating injection devices or preparing medication, and injections can be painful and create anxiety. Adherence to daily GH injections optimizes treatment benefit. Studies indicate that injection pens or needle-free devices enable easy self-injection by children, minimize medication reconstitution and storage requirements, and reduce injection pain. Newer GH delivery devices potentially encourage improved patient adherence. Reviewing features of GH devices will help nurses decide which GH device best fits the needs and abilities of pediatric patients. We searched recent medical literature about GH device development, about device-associated patient preferences and treatment adherence, and comparisons among GH devices. We concluded that improved awareness of the strengths and limitations of GH devices will enable nurses to guide families in selecting and using GH devices, improving adherence and outcomes, and helping children reach full growth potential.
生长激素缺乏症患儿自行注射生长激素(GH)可能会出现问题。他们在操作注射装置或准备药物时可能会有困难,而且注射会很疼并引发焦虑。坚持每日注射生长激素可使治疗效果最优化。研究表明,注射笔或无针装置便于儿童自行注射,可将药物复溶和储存需求降至最低,并减轻注射疼痛。新型生长激素给药装置可能会促使患者的依从性得到改善。审视生长激素装置的特点将有助于护士确定哪种生长激素装置最适合儿科患者的需求和能力。我们检索了近期有关生长激素装置研发、与装置相关的患者偏好和治疗依从性,以及生长激素装置之间比较的医学文献。我们得出结论,提高对生长激素装置优缺点的认识将使护士能够指导家庭选择和使用生长激素装置,提高依从性和治疗效果,并帮助儿童充分发挥生长潜力。