诊断与治疗重型再生障碍性贫血。

Diagnosing and treating severe aplastic anemia.

作者信息

McKee Natasha

机构信息

Natasha McKee practices dermatology at Western Montana Clinic in Missoula, Mont. The author has disclosed no potential conflicts of interest, financial or otherwise.

出版信息

JAAPA. 2015 Sep;28(9):36-8. doi: 10.1097/01.JAA.0000470975.32388.bc.

DOI:10.1097/01.JAA.0000470975.32388.bc

PMID:26302322

Abstract

Severe aplastic anemia is a disorder of stem cell failure, leading to pancytopenia. The condition is characterized by an impairment of the function of hematopoietic stem cells. Patients typically have fatigue, infections, and increased or unusual bleeding. A bone marrow biopsy establishes the diagnosis. Treatment includes hematopoietic stem cell transplant or immunosuppressive therapy.

摘要

严重再生障碍性贫血是一种干细胞衰竭性疾病，可导致全血细胞减少。该病的特征是造血干细胞功能受损。患者通常会出现疲劳、感染以及出血增加或异常。骨髓活检可确诊。治疗方法包括造血干细胞移植或免疫抑制治疗。