Verma Nishant, Rhyner John, Knight Bradley P
a Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Expert Rev Cardiovasc Ther. 2015;13(9):989-99. doi: 10.1586/14779072.2015.1071189.
The totally subcutaneous implantable cardioverter and defibrillator (S-ICD) represents the most innovative development in implantable cardioverter and defibrillator therapy in the last 15 years. Its development arose out of concern for the long-term complications of transvenous devices. Clinical trials have shown that it is a safe and effective device for patients at risk of sudden cardiac death. The lack of transvenous and intracardiac components makes it an attractive choice for young patients, those with limited vascular access and increased infectious risk. Despite these advantages, the current S-ICD system has limitations, including the inability to deliver cardiac pacing. Future programming and technologic advancements have the opportunity to dramatically improve the efficacy and broaden the patient population treated with the S-ICD.
全皮下植入式心脏复律除颤器(S-ICD)是过去15年中植入式心脏复律除颤器治疗领域最具创新性的进展。它的研发源于对经静脉装置长期并发症的关注。临床试验表明,对于有心脏性猝死风险的患者,它是一种安全有效的装置。由于不存在经静脉和心内组件,它对于年轻患者、血管通路有限以及感染风险增加的患者来说是一个有吸引力的选择。尽管有这些优点,但目前的S-ICD系统存在局限性,包括无法进行心脏起搏。未来的程控和技术进步有机会显著提高疗效,并扩大接受S-ICD治疗的患者群体。