Uddin Omar M, Haque Raqeeb, Sugrue Patrick A, Ahmed Yousef M, El Ahmadieh Tarek Y, Press Joel M, Koski Tyler, Fessler Richard G
Department of Neurological Surgery, Northwestern University Feinberg School of Medicine;
Rehabilitation Institute of Chicago; and.
J Neurosurg Spine. 2015 Dec;23(6):798-806. doi: 10.3171/2015.3.SPINE14560. Epub 2015 Aug 28.
Back pain is an increasing concern for the aging population. This study aims to evaluate if minimally invasive surgery presents cost-minimization benefits compared with open surgery in treating adult degenerative scoliosis.
Seventy-one patients with adult degenerative scoliosis received 2-stage, multilevel surgical correction through either a minimally invasive spine surgery (MIS) approach with posterior instrumentation (n = 38) or an open midline (Open) approach (n = 33). Costs were derived from hospital and rehabilitation charges. Length of stay, blood loss, and radiographic outcomes were obtained from electronic medical records. Functional outcomes were measured with Oswestry Disability Index (ODI) and visual analog scale (VAS) surveys.
Patients in both cohorts were similar in age (Age(MIS) = 65.68 yrs, Age(Open) = 63.58 yrs, p = 0.28). The mean follow-up was 18.16 months and 21.82 months for the MIS and Open cohorts, respectively (p = 0.34). MIS and Open cohorts had an average of 4.37 and 7.61 levels of fusion, respectively (p < 0.01). Total inpatient charges were lower for the MIS cohort ($269,807 vs $391,889, p < 0.01), and outpatient rehabilitation charges were similar ($41,072 vs $49,272, p = 0.48). MIS patients experienced reduced length of hospital stay (7.03 days vs 14.88 days, p < 0.01) and estimated blood loss (EBL) (EBL(MIS) = 470.26 ml, EBL(Open)= 2872.73 ml, p < 0.01). Baseline ODI scores were lower in the MIS cohort (40.03 vs 48.04, p = 0.03), and the cohorts experienced similar 1-year improvement (ΔODI(MIS) = -15.98, ΔODI(Open) = -21.96, p = 0.25). Baseline VAS scores were similar (VAS(MIS) = 6.56, VAS(Open)= 7.10, p = 0.32), but MIS patients experienced less reduction after 1 year (ΔVAS(MIS) = -3.36, ΔVAS(Open) = -4.73, p = 0.04). Preoperative sagittal vertical axis (SVA) were comparable (preoperative SVA(MIS) = 63.47 mm, preoperative SVA(Open) = 71.3 mm, p = 0.60), but MIS patients had larger postoperative SVA (postoperative SVA(MIS) = 51.17 mm, postoperative SVA(Open) = 28.17 mm, p = 0.03).
Minimally invasive surgery demonstrated reduced costs, blood loss, and hospital stays, whereas open surgery exhibited greater improvement in VAS scores, deformity correction, and sagittal balance. Additional studies with more patients and longer follow-up will determine if MIS provides cost-minimization opportunities for treatment of adult degenerative scoliosis.
背痛日益成为老龄人口关注的问题。本研究旨在评估在治疗成人退变性脊柱侧凸方面,与开放手术相比,微创手术是否具有成本最小化优势。
71例成人退变性脊柱侧凸患者接受了两阶段、多节段手术矫正,其中38例采用微创脊柱手术(MIS)后路器械置入法,33例采用开放中线(Open)入路法。费用来自医院和康复费用。住院时间、失血量和影像学结果从电子病历中获取。功能结果通过Oswestry功能障碍指数(ODI)和视觉模拟量表(VAS)调查进行测量。
两组患者年龄相似(MIS组年龄=65.68岁,Open组年龄=63.58岁,p=0.28)。MIS组和Open组的平均随访时间分别为18.16个月和21.82个月(p=0.34)。MIS组和Open组平均融合节段分别为4.37个和7.61个(p<0.01)。MIS组的总住院费用较低(269,807美元对391,889美元,p<0.01),门诊康复费用相似(41,072美元对49,272美元,p=0.48)。MIS组患者住院时间缩短(7.03天对14.88天,p<0.01),估计失血量(EBL)减少(MIS组EBL=470.26毫升,Open组EBL=2872.73毫升,p<0.01)。MIS组的基线ODI评分较低(40.03对48.04,p=0.03),两组1年改善情况相似(MIS组ΔODI=-15.98,Open组ΔODI=-21.96,p=0.25)。基线VAS评分相似(MIS组VAS=6.56,Open组VAS=7.10,p=0.32),但MIS组患者1年后降低幅度较小(MIS组ΔVAS=-3.36,Open组ΔVAS=-4.73,p=0.04)。术前矢状垂直轴(SVA)相当(术前MIS组SVA=63.47毫米,术前Open组SVA=71.3毫米,p=0.60),但MIS组患者术后SVA较大(术后MIS组SVA=51.17毫米,术后Open组SVA=28.17毫米,p=0.03)。
微创手术显示出成本、失血量和住院时间降低,而开放手术在VAS评分改善、畸形矫正和矢状面平衡方面表现更佳。更多患者参与和更长随访时间的进一步研究将确定MIS是否为成人退变性脊柱侧凸治疗提供成本最小化机会。