Laganà Antonio Simone, Condemi Irene, Retto Giovanni, Muscatello Maria Rosaria Anna, Bruno Antonio, Zoccali Rocco Antonio, Triolo Onofrio, Cedro Clemente
Department of Pediatric, Gynaecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy.
Department of Pediatric, Gynaecological, Microbiological and Biomedical Sciences, University of Messina, Messina, Italy.
Eur J Obstet Gynecol Reprod Biol. 2015 Nov;194:30-3. doi: 10.1016/j.ejogrb.2015.08.015. Epub 2015 Aug 15.
The present study was aimed to investigate quality of life, negative emotions, such as anger, anxiety and depression, and possible psychopathological comorbidity in patients affected by endometriosis.
We undertook a prospective, cohort study between October 2013 and February 2014. We selected patients with histologically confirmed ovarian endometriosis (Endometriosis Group) and with other benign adnexal diseases (Control Group) who underwent laparoscopic surgery. Participants underwent a psychometric assessment using the following self-report instruments: Symptom Checklist-90-R, State-Trait Anger Expression Inventory-2, Self-Rating Anxiety Scale, Self-Rating Depression Scale, Quality of Life Index.
The Endometriosis Group was formed by 166 patients (mean age: 36±6 yrs) matched with 48 controls (mean age: 38.4±12.8 yrs). Somatization (p=0.02), depression (p=0.01), sensitivity (p=0.04) and phobic anxiety (p=0.04) were higher in Endometriosis Group than in Control Group. Endometriosis Group was further characterized by significantly higher levels of anxiety than Control Group (p=0.03) as assessed by Self-Rating Anxiety Scale. Regarding Quality of Life Index, a significant health decline in Endometriosis Group compared with Control Group (p=0.008) was found.
Higher levels of somatization, depression, sensitivity and anxiety were found in Endometriosis Group compared with Control Group.
本研究旨在调查子宫内膜异位症患者的生活质量、愤怒、焦虑和抑郁等负面情绪以及可能存在的精神病理共病情况。
我们在2013年10月至2014年2月期间进行了一项前瞻性队列研究。我们选择了经组织学确诊为卵巢子宫内膜异位症的患者（子宫内膜异位症组）和患有其他良性附件疾病的患者（对照组），这些患者均接受了腹腔镜手术。参与者使用以下自我报告工具进行心理测量评估：症状自评量表-90-R、状态-特质愤怒表达量表-2、焦虑自评量表、抑郁自评量表、生活质量指数。
子宫内膜异位症组由166名患者组成（平均年龄：36±6岁），与48名对照组患者（平均年龄：38.4±12.8岁）匹配。子宫内膜异位症组的躯体化（p=0.02）、抑郁（p=0.01）、敏感（p=0.04）和恐惧焦虑（p=0.04）水平高于对照组。根据焦虑自评量表评估，子宫内膜异位症组的焦虑水平也显著高于对照组（p=0.03）。关于生活质量指数，发现子宫内膜异位症组与对照组相比健康状况显著下降（p=0.008）。
与对照组相比，子宫内膜异位症组的躯体化、抑郁、敏感和焦虑水平更高。
