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男性下尿路症状患者的终末滴沥:与国际前列腺症状评分及膀胱内前列腺突出的关系

Terminal dribbling in male patients with lower urinary tract symptoms: relationship with International Prostate Symptom Score and with intravesical prostatic protrusion.

作者信息

Kim Jae Heon, Shim Ji Sung, Choi Hoon, Moon Du Geon, Lee Jeong Gu, Kim Je Jong, Bae Jae Hyun, Park Jae Young

机构信息

Department of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

Department of Urology, Korea University Ansan Hospital, Ansan, Republic of Korea.

出版信息

BMC Urol. 2015 Aug 29;15:89. doi: 10.1186/s12894-015-0082-x.

DOI:10.1186/s12894-015-0082-x
PMID:26319937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4552983/
Abstract

BACKGROUND

Terminal dribbling is one of the lower urinary tract symptoms (LUTS) that has not been widely studied. The aim of this study was to investigate the associations between terminal dribbling (TD) and other parameters such as International Prostate Symptom Score (IPSS) and intravesical prostatic protrusion (IPP).

METHODS

Medical records of male patients with LUTS aged 40 years and older were prospectively collected. Data regarding TD defined by the International Continence Society standardization subcommittee, IPSS, prostate-specific antigen, total prostate volume, and IPP on transrectal ultrasonography were obtained. TD was confirmed by the subsequent uroflowmetry (uroflowmetry-confirmed TD). Logistic regression analysis was performed to identify the parameters affecting TD and uroflowmetry-confirmed TD.

RESULTS

Among the 578 men, 226 patients (39.1%) complained of TD and 157 patients (27.2%) had objective findings of TD on uroflowmetry. In the logistic regression analysis, IPSS voiding subscore were correlated with TD (Odds ratio 1.06). In addition, IPP was the only significant risk factor for uroflowmetry-confirmed TD (Odds ratio 2.83). Each question of IPSS is not correlated with TD or uroflowmetry-confirmed TD.

CONCLUSIONS

While the symptom of TD is well correlated with IPSS voiding subscore, objective evidence of TD on uroflowmetry had strong correlation with IPP. TD should be investigated further to reveal its clinical impact and guide a proper management.

摘要

背景

终末滴沥是一种尚未得到广泛研究的下尿路症状(LUTS)。本研究的目的是调查终末滴沥(TD)与其他参数之间的关联,如国际前列腺症状评分(IPSS)和膀胱内前列腺突出(IPP)。

方法

前瞻性收集40岁及以上LUTS男性患者的病历。获取国际尿控协会标准化小组委员会定义的关于TD、IPSS、前列腺特异性抗原、前列腺总体积以及经直肠超声检查的IPP的数据。通过随后的尿流率测定(尿流率测定确诊的TD)来确认TD。进行逻辑回归分析以确定影响TD和尿流率测定确诊的TD的参数。

结果

在578名男性中,226名患者(39.1%)主诉有TD,157名患者(27.2%)在尿流率测定时有TD的客观表现。在逻辑回归分析中,IPSS排尿子评分与TD相关(比值比1.06)。此外,IPP是尿流率测定确诊的TD的唯一显著危险因素(比值比2.83)。IPSS的每个问题与TD或尿流率测定确诊的TD均无相关性。

结论

虽然TD症状与IPSS排尿子评分密切相关,但尿流率测定中TD的客观证据与IPP密切相关。应进一步研究TD以揭示其临床影响并指导恰当的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a921/4552983/d805c22b6a23/12894_2015_82_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a921/4552983/d805c22b6a23/12894_2015_82_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a921/4552983/d805c22b6a23/12894_2015_82_Fig1_HTML.jpg

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