Ledet Johnathan, Groysman Vlada, Sami Naveed
Dermatology, NEA Baptist Clinic, Jonesboro, Arkansas.
Department of Dermatology, University of Alabama at Birmingham, EFH 414 1530 3rd Ave., South Birmingham, Alabama.
Dermatol Ther. 2016 Jan-Feb;29(1):28-31. doi: 10.1111/dth.12281. Epub 2015 Sep 2.
Woringer-Kolopp (WK) is a rare subtype of cutaneous T-cell lymphoma (CTCL) with limited treatment options. Bexarotene gel is a topical retinoid used in the treatment of CTCL. This report describes three female patients (mean age 66 years) with WK disease who had an effective treatment response to bexarotene 1% gel. This treatment could provide a safe alternative to other current treatment modalities which have higher risks of potential adverse effects and lack of access to other conventional treatments such as light therapy.
沃林格-科洛普(WK)是皮肤T细胞淋巴瘤(CTCL)的一种罕见亚型,治疗选择有限。贝沙罗汀凝胶是一种用于治疗CTCL的外用维甲酸类药物。本报告描述了三名患有WK疾病的女性患者(平均年龄66岁),她们对1%贝沙罗汀凝胶有有效的治疗反应。这种治疗方法可以为其他目前的治疗方式提供一种安全的替代方案,其他治疗方式潜在不良反应风险较高,且无法获得光疗等其他传统治疗。