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对不育男性进行或不进行睾丸游离的显微外科腹股沟下精索静脉结扎术的比较:睾丸游离是否为不必要的步骤。

Comparison between Microsurgical Subinguinal Varicocelectomy with and without Testicular Delivery for Infertile Men: Is Testicular Delivery an Unnecessary Procedure.

作者信息

Hou Yi, Zhang Ying, Zhang Yun, Huo Wei, Li Hai

机构信息

Department of Urology, China and Japan union hospital of Jilin University, 126 Xiantai Street, Changchun City, Jilin province, China.

出版信息

Urol J. 2015 Sep 4;12(4):2261-6.

Abstract

PURPOSE

Controversy still exists as to whether testicular delivery during microsurgical subinguinal varicocelecto­my (MSV) provides benefit to the patient or not. This study specifically compared the therapeutic effect of MSV with and without testicular delivery for the treatment of varicocele in a cohort of infertile men.

MATERIALS AND METHODS

We conducted a prospective, randomized, controlled study to evaluate the therapeutic efficacy of MSV with and without testicular delivery for the treatment of varicocele in infertile men. A total of 100 patients were specifically recruited using strict inclusion criteria to undergo MSV with testicular delivery (group 1, n = 50) or MSV without testicular delivery (group 2, n = 50). All patients were followed-up at 3, 6 and 12 months following surgery. Semen parameters, pregnancy and recurrence rates, and complications were monitored.

RESULTS

Mean surgical time for group 1 was significantly longer than group 2 (90.50 ± 15.60 min vs. 84.30 ± 15.58 min; P = .001). Sperm count and motility were significantly improved at the 12-month follow-up appoint­ment in both groups compared with pre-operative values, but were not significantly different at 3, 6, and 12 months when compared between the two treatment groups. The incidence of scrotal edema, and spermatic/testicular en­gorgement were higher in group 1 (both P = .001), although natural pregnancy rate was not significantly different between the two groups at the 12 month follow-up appointment (46% vs. 42%) (P = .817).

CONCLUSION

MSV with testicular delivery did not reduce the risk of recurrence and led to improved semen quality compared with MSV without testicular delivery. However, there was a higher risk of complication with this tech­nique, which must be borne in mind when considering the clinical implications of our dataset.

摘要

目的

关于显微外科腹股沟下精索静脉曲张切除术(MSV)术中是否进行睾丸移送对患者是否有益仍存在争议。本研究特别比较了在一组不育男性中,进行和不进行睾丸移送的MSV治疗精索静脉曲张的疗效。

材料与方法

我们进行了一项前瞻性、随机、对照研究,以评估进行和不进行睾丸移送的MSV治疗不育男性精索静脉曲张的疗效。使用严格的纳入标准专门招募了100例患者,进行带睾丸移送的MSV(第1组,n = 50)或不带睾丸移送的MSV(第2组,n = 50)。所有患者在术后3、6和12个月进行随访。监测精液参数、妊娠率、复发率和并发症。

结果

第1组的平均手术时间明显长于第2组(90.50±15.60分钟对84.30±15.58分钟;P = .001)。与术前值相比,两组在12个月随访时精子计数和活力均有显著改善,但在3、6和12个月时,两组之间比较无显著差异。第1组阴囊水肿和精索/睾丸充血的发生率较高(均P = .001),尽管在12个月随访时两组自然妊娠率无显著差异(46%对42%)(P = .817)。

结论

与不带睾丸移送的MSV相比,带睾丸移送的MSV并未降低复发风险,但精液质量有所改善。然而,该技术并发症风险较高,在考虑我们数据集的临床意义时必须牢记这一点。

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