Randazzo G, Sciuto L, Gaglio M, Trovato G M, Mazzone O
Medicina (Firenze). 1989 Oct-Dec;9(4):415-7.
Gilbert's syndrome is a frequent clinical condition with indirect hyperbilirubinemia, with controversial pathogenesis, nosography, and diagnostic criteria. Reliability of diagnostic test (caloric intake restriction and phenobarbital induction), as well as bilirubin modifications after physical exercise, were assessed in 7 patients with the disease. Phenobarbital induction appears to be the most suitable and reliable test for clinical non-invasive diagnosis of Gilbert's syndrome.
吉尔伯特综合征是一种常见的伴有间接胆红素血症的临床病症,其发病机制、疾病分类学及诊断标准存在争议。我们对7例患有该疾病的患者评估了诊断测试(热量摄入限制和苯巴比妥诱导)的可靠性,以及体育锻炼后的胆红素变化。苯巴比妥诱导似乎是吉尔伯特综合征临床无创诊断中最合适、最可靠的测试。