Al Shakarchi Julien, Stolba Jan, Houston J Graeme, Inston Nicholas
Department of Renal Surgery, University Hospital Birmingham, Birmingham - UK.
ReDVA Research Consortium, Dundee - UK.
J Vasc Access. 2016 Jan-Feb;17(1):40-6. doi: 10.5301/jva.5000467. Epub 2015 Sep 5.
Haemodialysis access-induced distal ischaemia (HAIDI) is a significant complication of vascular access creation, and has traditionally been difficult to manage without loss of access. Current treatment options include ligation, banding, distal revascularisation with interval ligation (DRIL), proximalisation of the arterial inflow (PAI) and revision using distal flow (RUDI). The purpose of this review was to evaluate the effectiveness of the different surgical techniques in the treatment of HAIDI.
Electronic databases were searched for studies assessing surgical techniques in the treatment of HAIDI in accordance with PRISMA. The primary outcome for the study was symptomatic relief for each technique, defined within each study. Secondary outcomes included comparison of early thrombosis rates following each different procedure.
Following strict inclusion/exclusion criteria by two reviewers, twenty-seven studies of surgical interventions were included and divided into subgroups for banding, DRIL, PAI and RUDI procedures. Both DRIL and banding procedures were found to have high rates of symptomatic relief. In addition, the DRIL has a significantly lower rate of early thrombosis than banding although the more recent papers seem to suggest that early thrombosis is less of a problem in banding. PAI and RUDI showed some promise but there were too few studies to be able to make any clear conclusions.
All four procedures have high success rate in relieving ischaemic symptoms with the DRIL procedure having a significantly better vascular access patency rate than other techniques, although further well designed studies are required to compare all four surgical techniques.
血液透析通路引起的远端缺血(HAIDI)是血管通路建立的一种重要并发症,传统上在不丧失通路的情况下难以处理。目前的治疗选择包括结扎、束带术、带间隔结扎的远端血管重建术(DRIL)、动脉流入近端化(PAI)以及使用远端血流的修复术(RUDI)。本综述的目的是评估不同手术技术治疗HAIDI的有效性。
根据PRISMA检索电子数据库中评估治疗HAIDI手术技术的研究。该研究的主要结局是每种技术的症状缓解情况,各研究中对此有明确界定。次要结局包括比较每种不同手术术后的早期血栓形成率。
经过两位评审员严格的纳入/排除标准筛选,纳入了27项手术干预研究,并分为束带术、DRIL、PAI和RUDI手术的亚组。发现DRIL和束带术的症状缓解率都很高。此外,DRIL的早期血栓形成率明显低于束带术,尽管最近的论文似乎表明束带术中早期血栓形成问题较小。PAI和RUDI显示出一定前景,但研究数量太少,无法得出任何明确结论。
所有这四种手术在缓解缺血症状方面成功率都很高,DRIL手术的血管通路通畅率明显优于其他技术,不过需要进一步设计完善的研究来比较所有这四种手术技术。