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用于减轻有源医疗植入物射频加热的磁共振成像(MRI)暴露的凸优化

Convex optimization of MRI exposure for mitigation of RF-heating from active medical implants.

作者信息

Córcoles Juan, Zastrow Earl, Kuster Niels

机构信息

Department of Electronic and Communication Technology, Universidad Autónoma de Madrid, C/ Francisco Tomás y Valiente, 11, Escuela Politécnica Superior, 28049 Madrid, Spain.

出版信息

Phys Med Biol. 2015 Sep 21;60(18):7293-308. doi: 10.1088/0031-9155/60/18/7293. Epub 2015 Sep 9.

Abstract

Local RF-heating of elongated medical implants during magnetic resonance imaging (MRI) may pose a significant health risk to patients. The actual patient risk depends on various parameters including RF magnetic field strength and frequency, MR coil design, patient's anatomy, posture, and imaging position, implant location, RF coupling efficiency of the implant, and the bio-physiological responses associated with the induced local heating. We present three constrained convex optimization strategies that incorporate the implant's RF-heating characteristics, for the reduction of local heating of medical implants during MRI. The study emphasizes the complementary performances of the different formulations. The analysis demonstrates that RF-induced heating of elongated metallic medical implants can be carefully controlled and balanced against MRI quality. A reduction of heating of up to 25 dB can be achieved at the cost of reduced uniformity in the magnitude of the B(1)(+) field of less than 5%. The current formulations incorporate a priori knowledge of clinically-specific parameters, which is assumed to be available. Before these techniques can be applied practically in the broader clinical context, further investigations are needed to determine whether reduced access to a priori knowledge regarding, e.g. the patient's anatomy, implant routing, RF-transmitter, and RF-implant coupling, can be accepted within reasonable levels of uncertainty.

摘要

在磁共振成像(MRI)过程中,细长型医用植入物的局部射频加热可能会给患者带来重大健康风险。实际的患者风险取决于多种参数,包括射频磁场强度和频率、磁共振线圈设计、患者的解剖结构、姿势和成像位置、植入物位置、植入物的射频耦合效率以及与局部感应加热相关的生物生理反应。我们提出了三种结合植入物射频加热特性的约束凸优化策略,以减少MRI过程中医用植入物的局部加热。该研究强调了不同公式的互补性能。分析表明,细长型金属医用植入物的射频感应加热可以得到谨慎控制,并在与MRI质量之间取得平衡。以B(1)(+)场幅度均匀性降低不到5%为代价,可实现高达25 dB的加热减少。当前的公式纳入了临床特定参数的先验知识,假定这些知识是可用的。在这些技术能够在更广泛的临床环境中实际应用之前,需要进一步研究以确定在合理水平的不确定性范围内,减少对诸如患者解剖结构、植入物路径、射频发射器和射频植入物耦合等先验知识的获取是否可以接受。

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