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[缺血性中风急性期颈动脉重建手术的结果]

[Outcomes of reconstructive operations on carotid arteries in acute period of ischaemic stroke].

作者信息

Mikhailov M S, Kirillov V I, Ridel V Yu, Alekseev A Yu, Novozhilov A V, Eidlin E G, Zelenkina N Yu, Solovov D V

机构信息

Department of Cardiovascular Surgery, Samara Municipal Clinical Hospital #1 named after N.I. Pirogov, Samara, Russia.

出版信息

Angiol Sosud Khir. 2015;21(3):118-23.

Abstract

Analysed herein are the results of surgical treatment of 55 patients who from June 2013 to August 2014 underwent a total of 56 reconstructive operations on carotid arteries during an acute period of ischaemic stroke. The operations were performed within the terms varying from 24 hours to 18 days after the onset of first symptoms of ischaemic stroke. The neurological status was assesses by the neurologist according to the NIH Stroke Severity Scale (USA) and the Modified Rankin Scale. Prior to operation neurological deficit in 18 patients corresponded to 4 points by the Rankin Scale. Carotid endarterectomy was performed in 55 patients, of these in 24 according to the eversion technique. In 10 patients eversion carotid endarterectomy was performed in combination with ICA resection. One patient was simultaneously subjected to eversion carotid endarterectomy and carotid-subclavian shunting bypass grafting. Carotid endarterectomy with autovenous-patch plasty was performed in 11 patients. Resection of the occluded internal carotid artery with plasty of the external carotid artery was carried out in 7 patients and resection of the internal carotid artery for pathological tortuosity was carried out in 2 patients. At discharge from hospital, regression of neurological symptomatology was noted in 46 (83%) patients. Nine (20%) patients showed complete restoration of neurological deficit, two (4%) patients were found to have increased manifestations of neurological deficit. In the postoperative period two patients died: one on postoperative day 24 from augmenting respiratory and cardiac failure, the other one on day 29 from augmenting renal insufficiency followed by cardiac failure. In both cases, autopsy revealed no signs of secondary impairment of cerebral circulation. Surgical interventions on carotid arteries performed at a multimodality vascular centre during the first 18 days after the development of ischaemic stroke in the majority of cases are accompanied and followed by regression of neurological deficit, being safe concerning the development of haemorrhagic transformation.

摘要

本文分析了2013年6月至2014年8月期间55例患者的手术治疗结果,这些患者在缺血性中风急性期共接受了56次颈动脉重建手术。手术在缺血性中风首次症状出现后的24小时至18天内进行。神经科医生根据美国国立卫生研究院卒中严重程度量表和改良Rankin量表评估神经状态。术前,18例患者的神经功能缺损根据Rankin量表评分为4分。55例患者接受了颈动脉内膜切除术,其中24例采用外翻技术。10例患者在进行外翻颈动脉内膜切除术的同时进行了颈内动脉切除术。1例患者同时接受了外翻颈动脉内膜切除术和颈动脉-锁骨下动脉分流搭桥术。11例患者进行了自体静脉补片成形术的颈动脉内膜切除术。7例患者进行了闭塞颈内动脉切除术并进行了颈外动脉成形术,2例患者因病理性迂曲进行了颈内动脉切除术。出院时,46例(83%)患者的神经症状有所缓解。9例(20%)患者神经功能缺损完全恢复,2例(4%)患者神经功能缺损表现加重。术后有2例患者死亡:1例于术后第24天死于呼吸和心力衰竭加重,另1例于第29天死于肾功能不全加重继而心力衰竭。在这两例中,尸检均未发现脑循环继发性损害的迹象。在缺血性中风发生后的前18天内,在多模式血管中心进行的颈动脉手术干预在大多数情况下伴随着神经功能缺损的缓解,并且在出血性转化的发生方面是安全的。

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