新石房蛤毒素与传统局部麻醉药：作用机制及显著效应部位 - Suppr

Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

作者信息

Rathmell James P, Strichartz Gary, Wanderer Jonathan

机构信息

Brigham and Women's Hospital/Harvard Medical School Brigham and Women's Health Care Vanderbilt University School of Medicine.

出版信息

Anesthesiology. 2015 Oct;123(4):A23. doi: 10.1097/01.anes.0000470956.02665.a6.

DOI:10.1097/01.anes.0000470956.02665.a6

PMID:26372144

Abstract

摘要

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Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

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Caramiphen-induced block of sodium currents and spinal anesthesia.

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Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages.

Mar Drugs. 2020 May 27;18(6):283. doi: 10.3390/md18060283.

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Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

作者信息

Rathmell James P, Strichartz Gary, Wanderer Jonathan

机构信息

Brigham and Women's Hospital/Harvard Medical School Brigham and Women's Health Care Vanderbilt University School of Medicine.

出版信息

Anesthesiology. 2015 Oct;123(4):A23. doi: 10.1097/01.anes.0000470956.02665.a6.

DOI:10.1097/01.anes.0000470956.02665.a6

PMID:26372144

Abstract

摘要

相似文献

Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

Anesthesiology. 2015 Oct;123(4):A23. doi: 10.1097/01.anes.0000470956.02665.a6.

Intrasphincteric neosaxitoxin injection: evidence of lower esophageal sphincter relaxation in achalasia.

Am J Gastroenterol. 2006 Nov;101(11):2667-8. doi: 10.1111/j.1572-0241.2006.00809_6.x.

First evidence of neosaxitoxin as a long-acting pain blocker in bladder pain syndrome.

Int Urogynecol J. 2015 Jun;26(6):853-8. doi: 10.1007/s00192-014-2608-2. Epub 2015 Jan 9.

Neosaxitoxin, a Paralytic Shellfish Poison toxin, effectively manages bucked shins pain, as a local long-acting pain blocker in an equine model.

Toxicon. 2018 Jan;141:15-17. doi: 10.1016/j.toxicon.2017.11.004. Epub 2017 Nov 13.

Local anaesthetics: 10 essentials.

Eur J Anaesthesiol. 2014 Nov;31(11):575-85. doi: 10.1097/EJA.0000000000000137.

Site-1 Sodium Channel Blockers as Local Anesthetics: Will Neosaxitoxin Supplant the Need for Continuous Nerve Blocks?

Anesthesiology. 2015 Oct;123(4):741-2. doi: 10.1097/ALN.0000000000000833.

Interactions of neosaxitoxin with the sodium channel of the frog skeletal muscle fiber.

J Gen Physiol. 1991 Mar;97(3):561-78. doi: 10.1085/jgp.97.3.561.

Neosaxitoxin as a local anesthetic: preliminary observations from a first human trial.

Anesthesiology. 2007 Feb;106(2):339-45. doi: 10.1097/00000542-200702000-00023.

Caramiphen-induced block of sodium currents and spinal anesthesia.

Eur J Pharmacol. 2015 Jan 5;746:213-20. doi: 10.1016/j.ejphar.2014.10.035. Epub 2014 Oct 29.

Long-lasting, reversible and non-neurotoxic inactivation of hippocampus activity induced by neosaxitoxin.

J Neurosci Methods. 2018 Oct 1;308:197-204. doi: 10.1016/j.jneumeth.2018.08.013. Epub 2018 Aug 11.

引用本文的文献

Novel Local Anesthetics in Clinical Practice: Pharmacologic Considerations and Potential Roles for the Future.

Anesth Pain Med. 2022 Feb 14;12(1):e123112. doi: 10.5812/aapm.123112. eCollection 2022 Feb.

Neosaxitoxin Inhibits the Expression of Inflammation Markers of the M1 Phenotype in Macrophages.

Mar Drugs. 2020 May 27;18(6):283. doi: 10.3390/md18060283.

Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

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Neosaxitoxin versus Traditional Local Anesthetics: Mechanism of Action and Sites of Notable Effect.

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