Kolovics Judit, Mattes Liuba Penova, Andersen Klaus Ejner, Beck-Nielsen Henning
Ugeskr Laeger. 2015 Sep 14;177(38):V01150054.
The development of squamous cell carcinoma in chronic and/or non-healing ulcers associated with necrobiosis lipoidica (NL) is rare, but should be considered in diabetic patients. NL is a non-infectious granulomatous degenerative skin disease. The prevalence of NL in diabetic patients is estimated to 0,3-1,2%. Awareness of malignant transformation potential within a plaque of NL is crucial for early diagnosis and easy radical treatment. A case from our outpatient diabetes clinic is presented.
在与类脂质渐进性坏死(NL)相关的慢性和/或不愈合溃疡中发生鳞状细胞癌的情况很少见,但糖尿病患者应予以考虑。NL是一种非感染性肉芽肿性退行性皮肤病。据估计,糖尿病患者中NL的患病率为0.3%-1.2%。认识到NL斑块内的恶性转化潜能对于早期诊断和易于进行根治性治疗至关重要。本文介绍了我们门诊糖尿病诊所的一个病例。