Nakamura Yukio, Kamimura Mikio, Ikegami Shota, Mukaiyama Keijiro, Komatsu Masatoshi, Uchiyama Shigeharu, Kato Hiroyuki
Department of Orthopaedic Surgery, Shinshu University School of Medicine, Matsumoto, Japan ; Department of Orthopaedic Surgery, Showa Inan General Hospital, Komagane, Japan.
Center of Osteoporosis and Spinal Disorders, Kamimura Clinic, Matsumoto, Japan.
Ther Clin Risk Manag. 2015 Sep 7;11:1361-5. doi: 10.2147/TCRM.S87274. eCollection 2015.
The syndrome of pregnancy- and lactation-associated osteoporosis is a rare disorder whose precise etiology and treatment are largely unknown. We herein report two such cases occurring in the early postpartum period that led to multiple fragility compression fractures. Combination therapy of vitamin D and vitamin K enabled a marked gradual increase in bone mineral density.
妊娠和哺乳期相关骨质疏松综合征是一种罕见的疾病,其确切病因和治疗方法在很大程度上尚不清楚。我们在此报告两例发生在产后早期并导致多处脆性压缩性骨折的病例。维生素D和维生素K联合治疗使骨密度显著逐渐增加。