Avcil Mucahit, Kapci Mucahit, Dagli Bekir, Omurlu Imran Kurt, Ozluer Emre, Karaman Kivanc, Yilmaz Ali, Zencir Cemil
Department of Emergency Medicine, School of Medicine, Adnan Menderes University Efeler/Aydin 09100, Turkey.
Department of Biostatistics, School of Medicine, Adnan Menderes University Efeler/Aydin 09100, Turkey.
Int J Clin Exp Med. 2015 Jul 15;8(7):10586-94. eCollection 2015.
The aim in this study was to compare the ultrasound estimation of the jugular vein diameter (IJVmax, IJVmin) and area (IJVarea), the height of the right internal jugular vein (CVPusg), the vena cava diameter (IVCmax, IVCmin), and the vena cava index (IVCindex) with direct estimation of central venous pressure (CVPinv).
Ultrasonography was performed on 37 nonventilated and 36 ventilated patients while monitoring central venous pressure. The IJV and IVC were measured during the respiratory cycle and the IJVarea and IVCindex were calculated. Tapering portion of the right IJV defined and height from this point to the sternal angle was used to estimate CVPusg.
A CVP of 10 mmHg was chosen as a clinically significant cutoff for high CVP, and 6 mmHg was chosen for low CVP estimation. The CVPusg, IJVmax and IJVmin correlated moderately with CVPinv (R² = 0.66, 0.53, and 0.54, respectively) whereas the IVCmax, IVCmin and IVCindex showed poor correlation (R² = 0.29, 0.32 and 0.27, respectively). The CVPusg cutoff value of 7 predicted CVPinv > 10 mmHg with sensitivity of 90%, specific-ity of 67.3% and predicted CVPinv < 6 mmHg with sensitivity of 77%, specificity of 68%. IJVmax, IJVmin, IJVarea and IVCmax showed high sensitivity (90.32%, 83.87%, 90.32%, and 93.10%, respectively) for low CVP levels. The IVCindex has high sensitivity (95.2%) and poor specificity (42.9%) for high CVP levels.
IVCindex and CVPusg has better diagnostic performance for estimating high CVP. IJVmax, IJV area, and IVCmax showed high sensitivity and NPV for low CVP levels.
本研究旨在比较超声估计颈静脉直径(IJVmax、IJVmin)和面积(IJVarea)、右颈内静脉高度(CVPusg)、腔静脉直径(IVCmax、IVCmin)以及腔静脉指数(IVCindex)与直接估计中心静脉压(CVPinv)的情况。
对37例未通气患者和36例通气患者进行超声检查,同时监测中心静脉压。在呼吸周期中测量颈内静脉和腔静脉,并计算IJVarea和IVCindex。确定右颈内静脉的逐渐变细部分,并以此点到胸骨角的高度来估计CVPusg。
选择10 mmHg的中心静脉压作为高中心静脉压的临床显著临界值,选择6 mmHg作为低中心静脉压估计值。CVPusg、IJVmax和IJVmin与CVPinv中度相关(R²分别为0.66、0.53和0.54),而IVCmax、IVCmin和IVCindex相关性较差(R²分别为0.29、0.32和0.27)。CVPusg临界值7预测CVPinv>10 mmHg的敏感性为90%,特异性为67.3%,预测CVPinv<6 mmHg的敏感性为77%,特异性为68%。IJVmax、IJVmin、IJVarea和IVCmax对低中心静脉压水平显示出高敏感性(分别为90.32%、83.87%、90.32%和93.10%)。IVCindex对高中心静脉压水平具有高敏感性(95.2%)和低特异性(42.9%)。
IVCindex和CVPusg在估计高中心静脉压方面具有更好的诊断性能。IJVmax、IJV面积和IVCmax对低中心静脉压水平显示出高敏感性和阴性预测值。