头孢曲松相关的急性胆囊增大——尿路感染患儿的意外诊断

Ceftriaxone-associated acute gallbladder enlargement - an unexpected diagnosis in the child with urinary tract infection.

作者信息

Krzemień Grażyna, Książczyk Tomasz, Szmigielska Agnieszka, Bombiński Przemysław, Roszkowska-Blaim Maria, Werner Bożena, Brzewski Michał

机构信息

Department of Pediatrics and Nephrology, The Medical University of Warsaw, Poland.

Department of Pediatrics and Cardiology, The Medical University of Warsaw, Poland.

出版信息

Dev Period Med. 2015 Apr-Jun;19(2):182-5.

PMID:26384120

Abstract

UNLABELLED

Biliary sludge and/or biliary pseudolithiasis occur in patients treated with ceftriaxone with prevalence of 3-57%. Biliary obstruction can be the cause of the acute gallbladder enlargement. It is a minor complication, that usually does not give clinical symptoms and resolves once the drug is discontinued. The authors present a case of a 5-month old boy treated for the acute pyelonephritis. Routine ultrasound, performed on the 5th day of treatment with ceftriaxone, showed gallbladder enlargement. In the consecutive studies small gallblader sludge was visible. Patient had no symptoms related to the gallbladder enlargement. Ultrasound performed 6 weeks from the drug discontinuation was completely normal.

CONCLUSIONS

Patients treated with ceftroiaxone should be monitored for biliary sludge and pseudolithiasis.

摘要

未标注

使用头孢曲松治疗的患者中会出现胆泥和/或胆假性结石，发生率为3%至57%。胆管梗阻可能是急性胆囊增大的原因。这是一种轻微并发症，通常不会出现临床症状，停药后即可缓解。作者报告了一例5个月大男孩因急性肾盂肾炎接受治疗的病例。在使用头孢曲松治疗的第5天进行的常规超声检查显示胆囊增大。在后续检查中可见小的胆囊胆泥。患者没有与胆囊增大相关的症状。停药6周后进行的超声检查完全正常。