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干细胞疗法:在泌尿外科的当前应用及潜力

Stem Cell Therapy: Current Applications and Potential for Urology.

作者信息

Wiafe Bridget, Metcalfe Peter D, Adesida Adetola B

机构信息

3-007 Li Ka Shing Centre for Health Research Innovation, University of Alberta, Edmonton, AB, Canada, T6G 2E1.

, 2C3.79 WMC, 8440-112 Street, Edmonton, AB, T6G 2B7, Canada.

出版信息

Curr Urol Rep. 2015 Nov;16(11):77. doi: 10.1007/s11934-015-0551-5.

Abstract

Stem cell therapy holds the potential to revolutionize the treatment of a number of chronic conditions. Stem cells ability to home in on injured sites of the body, stimulate angiogenesis, tissue regeneration, immunomodulation, anti-inflammatory, and anti-fibrotic factors have attracted their use in the treatment of many conditions. Urology has registered one of the highest experimental successes using stem cell therapy. However, the rate of clinical applications is comparatively lower. This review takes a look at our efforts so far and what needs to be done in order to maximize the clinical benefit we can derive from stem cells.

摘要

干细胞疗法有望彻底改变多种慢性病的治疗方式。干细胞能够归巢至身体的受伤部位,刺激血管生成、组织再生、免疫调节、抗炎和抗纤维化,这些特性促使其被用于多种疾病的治疗。泌尿外科在使用干细胞疗法方面取得了较高的实验成功率。然而,其临床应用率相对较低。本综述探讨了我们目前所做的努力,以及为了从干细胞中最大程度地获取临床益处还需要做些什么。

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