Development and testing of models of tuberculosis contact tracing in rural southern Africa.

SETTING

A regional hospital in rural Swaziland.

OBJECTIVES

To evaluate a hospital-based contact screening programme and test approaches to improve its effectiveness.

DESIGN

An evaluation and quality improvement study of tuberculosis (TB) contact tracing services.

RESULTS

Hospital-based TB contact tracing led to screening of 157 (24%) of 658 contacts; of these, 4 (2.5%) were diagnosed with TB. Of 68 contacts eligible for human immunodeficiency virus (HIV) testing and counselling, 45 (66%) were tested and 7/45 (16%) were identified as HIV-positive. Twelve (50%) of 24 screened contacts aged <5 years were provided isoniazid prophylaxis. Three enhanced models of TB contact tracing were piloted to screen contacts in the community. Although some enhanced models screened large numbers of contacts, no contacts were diagnosed with TB.

CONCLUSION

Contact tracing of household members conducted in TB clinics within hospital settings is effective in high-burden, low-income settings, and can be provided using current resources. Enhanced household contact tracing models that followed up contacts in the community were not found to be effective. Additional resources would be required to provide household TB contact tracing in the community.