中国上海出现邻硝基酚-β-D-半乳糖苷阴性宋内志贺菌。

Emergence of ONPG-negative Shigella sonnei in Shanghai, China.

作者信息

Wang Jian, Qiu Shaofu, Xu Xuebin, Su Wenli, Li Peng, Liang Beibei, Ma Qiuxia, Yang Chaojie, Qi Lihua, Li Hao, Yi Shengjie, Wu Zhihao, Wang Ligui, Hao Rongzhang, Song Hongbin, Sun Yansong

机构信息

Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing, China.

Shanghai Municipal Centre for Disease Control and Prevention, Shanghai, China.

出版信息

Diagn Microbiol Infect Dis. 2015 Dec;83(4):338-40. doi: 10.1016/j.diagmicrobio.2015.08.010. Epub 2015 Aug 20.

DOI:10.1016/j.diagmicrobio.2015.08.010

PMID:26403725

Abstract

Shigella sonnei has become predominant species causing shigellosis in Shanghai. Two hundred ninety-three S. sonnei were isolated in sentinel hospitals of Shanghai in 2011. We found an emergence of 8 strains of S. sonnei with negative phenotype for o-nitrophenyl-β-d-galactopyranoside in late August, which showed distinct pulsed-field gel electrophoresis patterns from the other 285 S. sonnei and had genes deletion in lac and mhp operons.

摘要

宋内志贺菌已成为上海引起志贺氏菌病的主要菌种。2011年在上海的哨点医院分离出293株宋内志贺菌。我们发现8月下旬出现了8株对邻硝基苯基-β-D-吡喃半乳糖苷呈阴性表型的宋内志贺菌，其脉冲场凝胶电泳图谱与其他285株宋内志贺菌不同，且在lac和mhp操纵子中存在基因缺失。