理解酸碱平衡紊乱。
Understanding Acid Base Disorders.
作者信息
Gomez Hernando, Kellum John A
机构信息
Department of Critical Care Medicine, Center for Critical Care Nephrology, The CRISMA Center, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
Department of Critical Care Medicine, Center for Critical Care Nephrology, The CRISMA Center, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA.
出版信息
Crit Care Clin. 2015 Oct;31(4):849-60. doi: 10.1016/j.ccc.2015.06.016. Epub 2015 Aug 13.
The concentration of hydrogen ions is regulated in biologic solutions. There are currently 3 recognized approaches to assess changes in acid base status. First is the traditional Henderson-Hasselbalch approach, also called the physiologic approach, which uses the relationship between HCO3(-) and Pco2; the second is the standard base excess approach based on the Van Slyke equation. The third approach is the quantitative or Stewart approach, which uses the strong ion difference and the total weak acids. This article explores the origins of the current concepts framing the existing methods to analyze acid base balance.
生物溶液中氢离子的浓度受到调节。目前有3种公认的评估酸碱状态变化的方法。第一种是传统的亨德森-哈塞尔巴尔赫方法，也称为生理学方法，它利用了HCO3(-)与Pco2之间的关系；第二种是基于范斯莱克方程的标准碱剩余方法。第三种方法是定量或斯图尔特方法，它使用强离子差和总弱酸。本文探讨了构成现有酸碱平衡分析方法的当前概念的起源。
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