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美国活体肾供体的体重趋势:器官共享联合网络数据库分析

Weight trends in United States living kidney donors: Analysis of the UNOS database.

作者信息

Sachdeva Mala, Rosen Lisa M, Varghese Jeny, Fishbane Steven, Molmenti Ernesto P

机构信息

Mala Sachdeva, Jeny Varghese, Steven Fishbane, Department of Medicine, Division of Kidney Diseases and Hypertension, North Shore University Hospital and LIJ Medical Center, Hofstra North Shore-LIJ School of Medicine, Great Neck, NY 11021, United States.

出版信息

World J Transplant. 2015 Sep 24;5(3):137-44. doi: 10.5500/wjt.v5.i3.137.

Abstract

AIM

To analyze the national trends associated with body mass index (BMI) and living kidney donation.

METHODS

Forty-seven thousand seven hundred and five adult living kidney donors as reported to the Organ Procurement and Transplantation Network from 1999 to 2011 were analyzed using their pre-donation BMI. Predictor variables of interest included age, gender, ethnicity, relationship, education status, and transplant region.

RESULTS

Sixteen thousand nine hundred and seventy-one of the living kidney donors were normal weight (35.6%); 19337 were overweight (40.5%); 9007 were mildly obese (18.9%); 1992 were moderate to morbidly obese (4.2%). Overweight and mildly obese kidney donors have increased through time by 12% and 20% every 5 years, respectively (P < 0.05). Donors 35-49 years of age, hispanic males or females and black females, those with high school diploma or general Education Degree, and biologically related or partner/spouses were more likely to be obese.

CONCLUSION

Over the past 13 years, the majority of living kidney donors have spanned the overweight to obese categories. Paralleling the national rise is an increase in overweight and mildly obese kidney donors. A fair number of moderate to morbidly obese living kidney donors are still allowed to donate.

摘要

目的

分析与体重指数(BMI)和活体肾捐赠相关的全国性趋势。

方法

对1999年至2011年器官获取与移植网络报告的47705名成年活体肾捐赠者,利用其捐赠前的BMI进行分析。感兴趣的预测变量包括年龄、性别、种族、关系、教育状况和移植区域。

结果

16971名活体肾捐赠者体重正常(35.6%);19337名超重(40.5%);9007名轻度肥胖(18.9%);1992名中度至病态肥胖(4.2%)。超重和轻度肥胖的肾捐赠者随时间推移分别每5年增加12%和20%(P<0.05)。35至49岁的捐赠者、西班牙裔男性或女性以及黑人女性、具有高中文凭或普通教育学位的人,以及有血缘关系或伴侣/配偶的人更有可能肥胖。

结论

在过去13年中,大多数活体肾捐赠者的体重范围从超重到肥胖。与全国范围内的上升趋势并行的是超重和轻度肥胖肾捐赠者数量的增加。仍有相当数量的中度至病态肥胖的活体肾捐赠者被允许捐赠。

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