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使用改良式下颌前移装置治疗的无牙颌阻塞性睡眠呼吸暂停患者上气道容积的变化

Changes in Upper Airway Volume in Edentulous Obstructive Sleep Apnea Patients Treated with Modified Mandibular Advancement Device.

作者信息

Tripathi Arvind, Gupta Ashutosh, Sarkar Sabyasachi, Tripathi Suryakant, Gupta Narendra

机构信息

Saraswati Dental College and Hospital, Lucknow, India.

Department of Prosthodontics, Saraswati Dental College and Hospital, Lucknow, India.

出版信息

J Prosthodont. 2016 Aug;25(6):453-8. doi: 10.1111/jopr.12335. Epub 2015 Sep 30.

Abstract

PURPOSE

This study was an attempt to verify the utility of complete dentures modified as a mandibular advancement device (MAD) in effecting expansion in pharyngeal volume to treat obstructive sleep apnea (OSA) in edentulous patients.

MATERIALS AND METHODS

The sample consisted of 17 patients (12 male, 5 female, average age 61 ± 4 years; BMI, 22 ± 5; apnea hypopnea index [AHI] 15 to 30). All patients had worn complete dentures for at least 1 year; all patients had the dentures modified to a MAD. Five variables were assessed preoperatively and 6 months after wearing the modified MADs. These variables were: sleep efficiency, AHI, oxygen desaturation events/hr., mean oxygen saturation, snoring index, and airway volume. This assessment was done by subjecting the patients to all-night polysomnography.

RESULTS

Without any prosthesis or device in the edentulous patients, the mean velopharyngeal volume was 8.05 ± 0.58 cm(3) , oropharyngeal volume was 2.14 ± 0.38 cm(3) , and hypopharyngeal volume was 3.26 ± 0.78 cm(3) . With complete dentures (unaltered) in the edentulous patients, the mean velopharyngeal, oropharyngeal, and hypopharyngeal volumes were 10.73 ± 0.98 cm(3) , 2.60 ± 0.48 cm(3) , and 4.31 ± 0.89 cm(3) , respectively. There was a statistically significant change in the airway volume following insertion of the complete dentures modified as MADs with velopharyngeal, oropharyngeal, and hypopharyngeal volume recorded as 11.76 ± 1.07 cm(3) , 3.33 ± 0.51 cm(3) , and 4.94 ± 0.83 cm(3) , respectively.

CONCLUSION

From the results obtained in this limited small sample study, it was inferred that the pharyngeal expansion induced by complete dentures modified as MADs effectively reduced symptoms of OSA. Increased volume was most pronounced in the velopharynx region followed by hypopharynx and oropharynx.

摘要

目的

本研究旨在验证改良为下颌前移装置(MAD)的全口义齿在扩大咽腔容积以治疗无牙颌患者阻塞性睡眠呼吸暂停(OSA)方面的效用。

材料与方法

样本包括17例患者(12例男性,5例女性,平均年龄61±4岁;体重指数[BMI],22±5;呼吸暂停低通气指数[AHI]为15至30)。所有患者佩戴全口义齿至少1年;所有患者的义齿均改良为MAD。在术前及佩戴改良MAD 6个月后评估五个变量。这些变量为:睡眠效率、AHI、每小时氧饱和度下降事件、平均氧饱和度、打鼾指数和气道容积。通过让患者进行整夜多导睡眠监测来完成此项评估。

结果

在无牙颌患者未佩戴任何假体或装置时,平均腭咽容积为8.05±0.58 cm³,口咽容积为2.14±0.38 cm³,下咽容积为3.26±0.78 cm³。在无牙颌患者佩戴全口义齿(未改良)时,平均腭咽、口咽和下咽容积分别为10.73±0.98 cm³、2.60±0.48 cm³和4.31±0.89 cm³。将全口义齿改良为MAD后插入,气道容积有统计学显著变化,腭咽、口咽和下咽容积分别记录为11.76±1.07 cm³、3.33±0.51 cm³和4.94±0.83 cm³。

结论

从这项有限的小样本研究获得的结果推断,改良为MAD的全口义齿引起的咽腔扩张有效减轻了OSA症状。容积增加在腭咽区域最为明显,其次是下咽和口咽。

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