Berretta Roberto, Dall'Asta Andrea, Merisio Carla, Monica Michela, Lori Letizia, Galli Letizia, Mautone Daniele, Frusca Tiziana
Department of Surgical Sciences, Obstetrics and Gynecology Unit, University of Parma, Parma, Italy.
Acta Biomed. 2015 Sep 14;86(2):176-80.
In this paper we summarize our experience in diagnosis and treatment of 402 retrospectively collected tubal EP and review the most recent topics from the literature. Systemic Methotrexate (MTX) was effective in 56 out of 65 patients (failure rate 13.8%), in whom hCG level was significantly lower when compared to the failure group (p<0,05); we performed 299 salpingectomies, 297 of whom through laparoscopic approach. MTX single-dose is safe and effective in eligible patients; surgery represents the treatment of most of the EPs, mainly through laparoscopic approach.
在本文中,我们总结了对402例回顾性收集的输卵管异位妊娠患者的诊断和治疗经验,并回顾了文献中的最新主题。65例患者中,全身应用甲氨蝶呤(MTX)治疗,56例有效(失败率13.8%),与失败组相比,这56例患者的hCG水平显著降低(p<0.05);我们进行了299例输卵管切除术,其中297例通过腹腔镜手术进行。单剂量MTX对符合条件的患者安全有效;手术是大多数输卵管异位妊娠的主要治疗方式,主要通过腹腔镜手术进行。