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会议报告——第九届IRIC癌症基因组学分子靶点国际研讨会

Meeting report--9th IRIC International Symposium on Molecular Targets in Cancer Genomics.

作者信息

Laumont Céline M, Haberl David, Ghugari Rahul, Tsao Sarah

机构信息

Institute for Research in Immunology and Cancer, Université de Montréal, P.O. Box 6128, Succursale Centre-Ville, Montreal, QC, Canada H3T 3J7.

Institute for Research in Immunology and Cancer, Université de Montréal, P.O. Box 6128, Succursale Centre-Ville, Montreal, QC, Canada H3T 3J7

出版信息

J Cell Sci. 2015 Oct 1;128(19):3521-4. doi: 10.1242/jcs.179051.

Abstract

Graduate students and postdoctoral fellows at the Institute for Research in Immunology and Cancer (IRIC) organized the 9th IRIC International Symposium on 14-15 May, 2015. The symposium was held at the IRIC, an ultra-modern research hub and training center located on the hilltop of the Université de Montréal campus in Montreal, Canada. This year's title was 'Molecular Targets in Cancer Genomics', reflecting the common interest of the IRIC student community. Through four broadly themed sessions, organizers sought to highlight the new generation of anti-cancer strategies including targeted therapies directed against actionable cancer-specific mutations, and immunotherapies, which enhance immune responses against cancer. Both targeted and immunotherapies are tailored to cancer-specific features, and require precise knowledge of cancer cells, from their genome to their proteome. The focus of this symposium was on translating the molecular basis of cancer into a functional understanding of aberrant pathways, and to uncover novel targets to be exploited for cancer therapeutic strategies.

摘要

2015年5月14日至15日,免疫与癌症研究所(IRIC)的研究生和博士后组织了第九届IRIC国际研讨会。该研讨会在IRIC举行,IRIC是一个超现代的研究中心和培训中心,位于加拿大蒙特利尔市蒙特利尔大学校园山顶。今年的主题是“癌症基因组学中的分子靶点”,反映了IRIC学生群体的共同兴趣。通过四个主题广泛的会议,组织者试图突出新一代抗癌策略,包括针对可操作的癌症特异性突变的靶向治疗和增强针对癌症的免疫反应的免疫治疗。靶向治疗和免疫治疗都针对癌症的特定特征,需要对癌细胞从基因组到蛋白质组有精确的了解。本次研讨会的重点是将癌症的分子基础转化为对异常通路的功能性理解,并发现可用于癌症治疗策略的新靶点。

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