Tang Xu-Dong, Yue Ya-Jie, Wang Wei, Li Nan, Shen Zhong-Yuan
Jiangsu University of Science and Technology, Zhenjiang 212018, Jiangsu, China; Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang 212018, Jiangsu, China; Key Laboratory of Genetic Improvement of Silkworm and Mulberry of Agricultural Ministry, Zhenjiang 212003, Jiangsu, China.
Jiangsu University of Science and Technology, Zhenjiang 212018, Jiangsu, China; Sericultural Research Institute, Chinese Academy of Agricultural Sciences, Zhenjiang 212018, Jiangsu, China; Key Laboratory of Genetic Improvement of Silkworm and Mulberry of Agricultural Ministry, Zhenjiang 212003, Jiangsu, China.
Gene. 2016 Jan 15;576(1 Pt 1):60-3. doi: 10.1016/j.gene.2015.09.073. Epub 2015 Sep 30.
With the recent availability of the genomes of many viruses and the silkworm, Bombyx mori, as well as a variety of Basic Local Alignment Search Tool (BLAST) programs, a new opportunity to gain insight into the interaction of viruses with the silkworm is possible. This study aims to determine the possible existence of sequence identities between the genomes of viruses and the silkworm and attempts to explain this phenomenon. BLAST searches of the genomes of viruses against the silkworm genome were performed using the resources of the National Center for Biotechnology Information. All studied viruses contained variable numbers of short regions with sequence identity to the genome of the silkworm. The short regions of sequence identity in the genome of the silkworm may be derived from the genomes of viruses in the long history of silkworm-virus interaction. This study is the first to compare these genomes, and may contribute to research on the interaction between viruses and the silkworm.
随着近期许多病毒以及家蚕（Bombyx mori）基因组的可得性，还有各种基本局部比对搜索工具（BLAST）程序的出现，深入了解病毒与家蚕相互作用有了新的契机。本研究旨在确定病毒基因组与家蚕基因组之间是否可能存在序列同一性，并尝试解释这一现象。利用美国国立生物技术信息中心的资源，对病毒基因组与家蚕基因组进行了BLAST搜索。所有研究的病毒都包含数量不等的与家蚕基因组具有序列同一性的短区域。家蚕基因组中序列同一性的短区域可能源自病毒与家蚕长期相互作用历史中的病毒基因组。本研究首次对这些基因组进行比较，可能有助于病毒与家蚕相互作用的研究。
