白细胞介素-18缺失可抑制小鼠缺氧诱导的肺动脉高压。 - Suppr

Interleukin-18 disruption suppresses hypoxia-induced pulmonary artery hypertension in mice.

作者信息

Morisawa Daisuke, Hirotani Shinichi, Oboshi Makiko, Nishimura Koichi, Sawada Hisashi, Eguchi Akiyo, Okuhara Yoshitaka, Iwasaku Toshihiro, Naito Yoshiro, Mano Toshiaki, Okamura Haruki, Masuyama Tohru

机构信息

Cardiovascular Division, Department of Internal Medicine, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan.

出版信息

Int J Cardiol. 2016 Jan 1;202:522-4. doi: 10.1016/j.ijcard.2015.09.118. Epub 2015 Oct 3.

DOI:10.1016/j.ijcard.2015.09.118

PMID:26440469

Abstract

摘要

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相似文献

Interleukin-18 disruption suppresses hypoxia-induced pulmonary artery hypertension in mice.

Int J Cardiol. 2016 Jan 1;202:522-4. doi: 10.1016/j.ijcard.2015.09.118. Epub 2015 Oct 3.

Cardiovasc Res. 2013 Dec 1;100(3):363-73. doi: 10.1093/cvr/cvt214. Epub 2013 Sep 16.

Interleukin-6 causes mild pulmonary hypertension and augments hypoxia-induced pulmonary hypertension in mice.

Chest. 2005 Dec;128(6 Suppl):572S-573S. doi: 10.1378/chest.128.6_suppl.572S-a.

Dominant negative mutation of the TGF-beta receptor blocks hypoxia-induced pulmonary vascular remodeling.

J Appl Physiol (1985). 2006 Feb;100(2):564-71. doi: 10.1152/japplphysiol.00595.2005. Epub 2005 Oct 13.

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Biochem Biophys Res Commun. 2015 Sep 25;465(3):356-62. doi: 10.1016/j.bbrc.2015.08.002. Epub 2015 Aug 12.

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Circulation. 2013 Jan 1;127(1):115-25. doi: 10.1161/CIRCULATIONAHA.112.133413. Epub 2012 Nov 13.

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Arterioscler Thromb Vasc Biol. 2013 Dec;33(12):2780-91. doi: 10.1161/ATVBAHA.113.301357. Epub 2013 Oct 17.

Involvement of Gax gene in hypoxia-induced pulmonary hypertension, proliferation, and apoptosis of arterial smooth muscle cells.

Am J Respir Cell Mol Biol. 2011 Jan;44(1):66-73. doi: 10.1165/rcmb.2008-0442OC. Epub 2010 Feb 16.

PAR-2 inhibition reverses experimental pulmonary hypertension.

Circ Res. 2012 Apr 27;110(9):1179-91. doi: 10.1161/CIRCRESAHA.111.257568. Epub 2012 Mar 29.

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Pulm Pharmacol Ther. 2011 Dec;24(6):638-46. doi: 10.1016/j.pupt.2011.09.003. Epub 2011 Sep 24.

引用本文的文献

Alveolar hypoxia induces organ-specific inflammasome-related inflammation in male mouse lungs.

Physiol Rep. 2024 Jul;12(14):e16143. doi: 10.14814/phy2.16143.

Inflammation and immunity in the pathogenesis of hypoxic pulmonary hypertension.

Front Immunol. 2023 May 5;14:1162556. doi: 10.3389/fimmu.2023.1162556. eCollection 2023.

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Curr Hypertens Rep. 2022 Nov;24(11):547-562. doi: 10.1007/s11906-022-01214-4. Epub 2022 Jul 7.

Emerging Role of the Inflammasome and Pyroptosis in Hypertension.

Int J Mol Sci. 2021 Jan 21;22(3):1064. doi: 10.3390/ijms22031064.

IL-18 mediates sickle cell cardiomyopathy and ventricular arrhythmias.

Blood. 2021 Mar 4;137(9):1208-1218. doi: 10.1182/blood.2020005944.

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ACS Pharmacol Transl Sci. 2020 Jul 1;3(4):598-612. doi: 10.1021/acsptsci.0c00048. eCollection 2020 Aug 14.

Cytokines trigger disruption of endothelium barrier function and p38 MAP kinase activation in -silenced human lung microvascular endothelial cells.

Pulm Circ. 2019 Oct 23;9(4):2045894019883607. doi: 10.1177/2045894019883607. eCollection 2019 Oct-Dec.

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Mediators Inflamm. 2019 Jul 22;2019:8691294. doi: 10.1155/2019/8691294. eCollection 2019.

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Br J Pharmacol. 2019 Jun;176(12):1880-1896. doi: 10.1111/bph.14375. Epub 2018 Jun 27.

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Am J Physiol Lung Cell Mol Physiol. 2016 Nov 1;311(5):L811-L831. doi: 10.1152/ajplung.00302.2016. Epub 2016 Sep 2.

Interleukin-18 disruption suppresses hypoxia-induced pulmonary artery hypertension in mice.

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