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腹腔镜辅助阴道子宫切除术治疗盆腔器官脱垂的手术并发症系统评估

Systematic assessment of surgical complications in laparoscopically assisted vaginal hysterectomy for pelvic organ prolapse.

作者信息

Mothes Anke R, Radosa Marc P, Runnebaum Ingo B

机构信息

Department of Gynaecology, Jena University Hospital, Friedrich-Schiller-University Jena, Bachstreet 18, D-07743 Jena, Germany.

Department of Gynaecology, Jena University Hospital, Friedrich-Schiller-University Jena, Bachstreet 18, D-07743 Jena, Germany.

出版信息

Eur J Obstet Gynecol Reprod Biol. 2015 Nov;194:228-32. doi: 10.1016/j.ejogrb.2015.09.026. Epub 2015 Sep 28.

Abstract

OBJECTIVE

To assess patient safety and complication rates in native tissue vaginal prolapse repair combined with laparoscopically assisted vaginal hysterectomy and prophylactic salpingectomy/salpingoophorectomy.

STUDY DESIGN

This was a single-centre retrospective study conducted at the University Hospital, Urogynaecological Unit, with a certified urogynaecological surgeon. A cohort of 321 consecutive patients received laparoscopically assisted vaginal hysterectomy for pelvic organ prolapse grade II-IV combined with defect-specific vaginal native tissue repair. Analysis of the total cohort and subgroups according to prolapse grade and concomitant laparoscopic procedures was performed. Student's t-tests and chi-squared tests were used for descriptive statistical analysis. Surgical complications were classified using the Clavien-Dindo (CD) classification system of surgical complications.

RESULTS

Complications were classified as CD I (1.87%), CD II (13.39%), CD IIIa (0.62%), and CD IIIb (1.87%); no CD IV or CD V complication occurred. One (0.31%) intraoperative bladder lesion, but no rectal lesion, ureter lesion, or intraoperative haemorrhage requiring blood transfusion, was noted. The overall morbidity rate, including the intraoperative bladder lesion and the CD I complication, was 18.06%. All (n=321) patients underwent prophylactic salpingectomy. Additional oophorectomy was performed in 222 post-menopausal patients. Pelvic adhesions were found in 123 (38.31%) patients and 148 (46%) patients presented grade IV prolapse. Operating time was longer for grade IV than for grade II/III prolapse (p<0.01), but CD III complication rates did not differ between these groups. Operating time was longer when laparoscopic adhesiolysis was performed (p=0.025), but this factor did not affect CD III complication rates.

CONCLUSIONS

The combination of vaginal site-specific prolapse repair with laparoscopically assisted hysterectomy leads to low complication rates. Prophylactic salpingectomy or salpingoophorectomy can be performed safely in combination with hysterectomy for pelvic organ prolapse. In terms of surgical safety laparoscopy seems to be a meaningful addition to vaginal native tissue prolapse surgery.

摘要

目的

评估天然组织阴道脱垂修复联合腹腔镜辅助阴道子宫切除术及预防性输卵管切除术/输卵管卵巢切除术时的患者安全性及并发症发生率。

研究设计

这是一项在大学医院泌尿妇科病房由一名获得认证的泌尿妇科外科医生开展的单中心回顾性研究。一组321例连续患者接受了腹腔镜辅助阴道子宫切除术,用于治疗II-IV级盆腔器官脱垂,并结合特定缺损的阴道天然组织修复。根据脱垂分级和同期腹腔镜手术对整个队列及亚组进行了分析。采用学生t检验和卡方检验进行描述性统计分析。手术并发症采用Clavien-Dindo(CD)手术并发症分类系统进行分类。

结果

并发症分类为CD I(1.87%)、CD II(13.39%)、CD IIIa(0.62%)和CD IIIb(1.87%);未发生CD IV或CD V级并发症。记录到1例(0.31%)术中膀胱损伤,但未发现直肠损伤、输尿管损伤或需要输血的术中出血。包括术中膀胱损伤和CD I级并发症在内的总体发病率为18.06%。所有(n = 321)患者均接受了预防性输卵管切除术。222例绝经后患者进行了额外的卵巢切除术。123例(38.31%)患者发现盆腔粘连,148例(46%)患者为IV级脱垂。IV级脱垂的手术时间比II/III级脱垂更长(p<0.01),但这些组之间的CD III级并发症发生率无差异。进行腹腔镜粘连松解术时手术时间更长(p = 0.025),但该因素不影响CD III级并发症发生率。

结论

阴道特定部位脱垂修复与腹腔镜辅助子宫切除术相结合导致并发症发生率较低。预防性输卵管切除术或输卵管卵巢切除术可与子宫切除术安全地联合用于治疗盆腔器官脱垂。就手术安全性而言,腹腔镜检查似乎是阴道天然组织脱垂手术中有意义的补充。

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