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钝性胸部创伤后冠状动脉夹层导致未被发现的急性心肌梗死死亡。

Death from undetected acute myocardial infarction secondary to coronary artery dissection after blunt thoracic trauma.

作者信息

Puanglumyai Supot, Thamtakerngkit Somboon, Lekawanvijit Suree

机构信息

Department of Forensic Medicine, Chonburi Hospital, Chonburi, Thailand.

Department of Forensic Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Cardiovasc Pathol. 2016 Mar-Apr;25(2):169-71. doi: 10.1016/j.carpath.2015.09.004. Epub 2015 Sep 21.

Abstract

Blunt thoracic trauma is a common occurrence in automobile accidents. Acute myocardial infarction (AMI) caused by coronary dissection following blunt thoracic trauma is rare. We report a case of healthy 24-year-old man with a history of blunt thoracic injury with subsequent undetected AMI who died of acute decompensated heart failure 4 days after the insult. The autopsy findings showed a 90% luminal narrowing of the left anterior descending coronary artery by dissecting hematoma, 3 cm in length. The myocardium revealed transmural myocardial infarction affecting apex, most part of left ventricular free wall, and interventricular septum. Both lungs were heavy, wet, and noncrepitant. Histological findings of the infarcted myocardium were consistent with 3-5 days post-AMI. Sections from both lungs revealed massive pulmonary edema, reflecting acute decompensated heart failure following a large AMI secondary to coronary dissection. Blunt thoracic trauma may obscure typical chest pain associated with cardiac ischemia especially in cases with a high tolerance for pain.

摘要

钝性胸部创伤在汽车事故中很常见。钝性胸部创伤后因冠状动脉夹层导致的急性心肌梗死(AMI)很罕见。我们报告一例24岁健康男性,有钝性胸部损伤史,随后未被发现患有AMI,在受伤4天后死于急性失代偿性心力衰竭。尸检结果显示,左前降支冠状动脉因夹层血肿导致管腔狭窄90%,长度为3厘米。心肌显示透壁性心肌梗死,累及心尖、左心室游离壁大部分和室间隔。双肺沉重、湿润且无捻发音。梗死心肌的组织学结果与AMI后3 - 5天一致。双肺切片显示大量肺水肿,反映了冠状动脉夹层继发大面积AMI后的急性失代偿性心力衰竭。钝性胸部创伤可能掩盖与心脏缺血相关的典型胸痛,尤其是在对疼痛耐受性高的情况下。

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