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儿童鼾症缓解对其社会心理功能的纵向影响。

Longitudinal Impact of Resolution of Snoring in Young Children on Psychosocial Functioning.

机构信息

The Ritchie Center, Hudson Institute of Medical Research, Melbourne, Australia; Department of Pediatrics, Monash University, Melbourne, Australia.

The Ritchie Center, Hudson Institute of Medical Research, Melbourne, Australia; Department of Pediatrics, Monash University, Melbourne, Australia.

出版信息

J Pediatr. 2015 Dec;167(6):1272-9.e1. doi: 10.1016/j.jpeds.2015.09.016. Epub 2015 Oct 9.

Abstract

OBJECTIVE

To determine whether sustained resolution of sleep disordered breathing (SDB) in young children, either because of treatment or spontaneous recovery, predicted long-term improvements in quality of life, family functioning, and parental stress.

STUDY DESIGN

Children diagnosed with primary snoring (n = 16), mild obstructive sleep apnea (OSA, n = 11), moderate-severe (MS) OSA (n = 8), and healthy nonsnoring controls (n = 25) at ages 3-5 years underwent repeat polysomnography at 6-8 years. Parents completed quality of life and parental stress questionnaires at both time points. Resolution of SDB was determined as obstructive apnea hypopnea index (OAHI) ≤1 event/hour, or absence of snoring during polysomnography or on parent report. Linear mixed-model analyses determined the effects of resolution on psychosocial morbidity. OAHI was used to determine the predictive value of changes in SDB severity on psychosocial outcomes.

RESULTS

Fifty percent of primary snoring, 45% mild OSA, and 63% MS OSA resolved, of which 67% received treatment. Children originally diagnosed with SDB continued to show significant psychosocial impairments compared with nonsnoring controls, irrespective of resolution. A reduction in OAHI predicted improvements in physical symptoms, school functioning, family worry and family relationships, and stress related to a difficult child.

CONCLUSIONS

Treatment was more likely to result in resolution of SDB if original symptoms were MS. Children originally diagnosed with SDB, irrespective of resolution, continued to experience psychosocial dysfunction suggesting additional interventions are required.

摘要

目的

确定儿童睡眠呼吸障碍(SDB)是否持续缓解(无论是因为治疗还是自然恢复),是否可以预测生活质量、家庭功能和父母压力的长期改善。

研究设计

3-5 岁时被诊断为单纯性打鼾(n=16)、轻度阻塞性睡眠呼吸暂停(OSA,n=11)、中重度(MS)OSA(n=8)和健康不打鼾对照(n=25)的儿童,在 6-8 岁时进行重复多导睡眠图检查。父母在两个时间点都完成了生活质量和父母压力问卷。SDB 缓解定义为阻塞性呼吸暂停低通气指数(OAHI)≤1 次/小时,或多导睡眠图检查期间无打鼾或父母报告无打鼾。线性混合模型分析确定缓解对心理社会发病率的影响。OAHI 用于确定 SDB 严重程度变化对心理社会结局的预测价值。

结果

50%的单纯性打鼾、45%的轻度 OSA 和 63%的 MS OSA 缓解,其中 67%接受了治疗。与不打鼾的对照组相比,最初被诊断为 SDB 的儿童,无论是否缓解,仍表现出显著的心理社会障碍。OAHI 的降低预测了身体症状、学校功能、家庭担忧和家庭关系以及与困难儿童相关的压力的改善。

结论

如果原始症状为 MS,则治疗更有可能导致 SDB 缓解。无论是否缓解,最初被诊断为 SDB 的儿童继续经历心理社会功能障碍,这表明需要额外的干预措施。

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