Laiyemo R, Dudill W, Jones S E, Browne H
a Department of Obstetrics and Gynaecology , Kingsmill Hospital , Sutton in Ashfield , UK.
b Department of Obstetrics and Gynaecology , Bradford Royal Infirmary , Bradford , UK.
J Obstet Gynaecol. 2016;36(2):223-6. doi: 10.3109/01443615.2015.1050649. Epub 2015 Oct 14.
We aimed to determine the incidence of endometrial cancer in a cohort of postmenopausal women with thickened endometrium but no bleeding referred for hysteroscopy and determine the risk estimate of cancer using a cut-off of > 11 mm. This retrospective study of asymptomatic postmenopausal women with thickened endometrium on trans-vaginal scan referred for hysteroscopy was performed using data from 2008 to 2010. In total 63 women were identified. 2 cases of endometrial cancer were identified with an incidence of 3.17%. 22 cases had endometrial thickness (ET) > 11 mm of which 2 were malignant giving a risk estimate for endometrial cancer of 9.1%. 61 women had benign pathology, 40.98% had atrophic endometrium and 59.02% had benign polyp. In conclusion, the incidence of endometrial cancer in postmenopausal women with thickened endometrium on transvaginal scan without vaginal bleeding is low and ET of 11 mm or more seems realistic to use as a cut-off for referral for hysteroscopy.
我们旨在确定一群子宫内膜增厚但无出血且因宫腔镜检查前来就诊的绝经后女性中子宫内膜癌的发病率，并使用大于11毫米的临界值来确定癌症的风险评估。这项针对经阴道扫描显示子宫内膜增厚且因宫腔镜检查前来就诊的无症状绝经后女性的回顾性研究，使用了2008年至2010年的数据。总共确定了63名女性。确诊2例子宫内膜癌，发病率为3.17%。22例子宫内膜厚度（ET）大于11毫米，其中2例为恶性，子宫内膜癌的风险评估为9.1%。61名女性病理结果为良性，40.98%为萎缩性子宫内膜，59.02%为良性息肉。总之，经阴道扫描显示子宫内膜增厚且无阴道出血的绝经后女性中子宫内膜癌的发病率较低，11毫米或以上的子宫内膜厚度似乎可作为转诊进行宫腔镜检查的合理临界值。
