Lin Henry, Lema Gareth M C, Yoganathan Pradeepa
Department of Ophthalmology, Ross Eye Institute, University at Buffalo, The State University of New York, Buffalo, New York.
Retina. 2016 Apr;36(4):750-7. doi: 10.1097/IAE.0000000000000798.
To identify prognostic indicators of postoperative visual acuity and retinal detachment (RD) in open globe injuries.
Retrospective review of 50 adult open globe injuries between September 2011 and March 2014. Hierarchical multivariable regression was used to evaluate relationships among injury characteristics, postoperative visual acuity, and RD after age adjustment.
Mean participant age was 46.2 years, and mean follow-up was 1.2 years. Blunt trauma accounted for 58% of injuries (29/50), and the wound extended posteriorly into sclera in 64% of cases (32/50). The retinal detachment occurred in 40% of patients (20/50), 95% of whom had developed vitreous hemorrhage (19/20). Multivariable regression revealed that preoperative visual acuity (P = 0.0010), posterior wound extension (P = 0.022), and RD (P = 0.0038) independently predicted postoperative visual acuity. No other injury characteristic was related to postoperative visual acuity after adjustment for preoperative visual acuity. Vitreous hemorrhage predicted RD (P < 0.001), and further consideration of preoperative visual acuity and other variables did not improve model fit. Moreover, among patients who underwent RD repair (n = 13), earlier vitrectomy after vitreous hemorrhage diagnosis (≤12 days) was associated with fewer macula-off RDs (P = 0.018) and better postoperative visual acuity (P = 0.0055).
Preoperative visual acuity, posterior wound extension, and RD significantly influenced postoperative visual acuity after open globe injury. Vitreous hemorrhage predicted RD, and prompt intervention after detection may improve visual outcomes.
确定开放性眼球损伤术后视力及视网膜脱离(RD)的预后指标。
回顾性分析2011年9月至2014年3月期间50例成人开放性眼球损伤病例。采用分层多变量回归分析在年龄调整后评估损伤特征、术后视力和视网膜脱离之间的关系。
参与者平均年龄为46.2岁,平均随访时间为1.2年。钝挫伤占损伤的58%(29/50),64%的病例(32/50)伤口向后延伸至巩膜。40%的患者(20/50)发生视网膜脱离,其中95%(19/20)伴有玻璃体积血。多变量回归显示,术前视力(P = 0.0010)、伤口向后延伸(P = 0.022)和视网膜脱离(P = 0.0038)独立预测术后视力。在调整术前视力后,没有其他损伤特征与术后视力相关。玻璃体积血可预测视网膜脱离(P < 0.001),进一步考虑术前视力和其他变量并不能改善模型拟合。此外,在接受视网膜脱离修复的患者(n = 13)中,玻璃体积血诊断后较早进行玻璃体切除术(≤12天)与黄斑脱离性视网膜脱离较少(P = 0.018)及术后视力较好(P = 0.0055)相关。
术前视力、伤口向后延伸和视网膜脱离显著影响开放性眼球损伤术后视力。玻璃体积血可预测视网膜脱离,检测后及时干预可能改善视力预后。