Department of Toxicology, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Department of Occupational and Environmental Health, School of Public Health, Guangxi Medical University, Nanning, Guangxi, China.
Sci Total Environ. 2016 Jan 15;541:1348-1354. doi: 10.1016/j.scitotenv.2015.10.038. Epub 2015 Nov 11.
Levels of methyl tertiary-butyl ether (MTBE) in occupational air, ambient air, and drinking water in Nanning, South China, were investigated, and then their potential health risks to occupational workers and the general public were evaluated. Results show that the MTBE concentration in occupational air from 13 service stations was significantly higher than that in ambient air from residential areas (p<0.0001); both are far lower than the threshold limit value-time weighted average of MTBE regulated in the United States (US). The drinking water samples from household taps yielded detectable MTBE in the range of 0.04-0.33 μg/L, which is below the US drinking water standard of 20-40 μg/L. The non-carcinogenic risk of MTBE from air inhalation may be negligible because the calculated hazard quotient was less than 1. The mean MTBE lifetime cancer risk was within the acceptable limit of 1 × 10(-6) to 1 × 10(-4), but the lifetime cancer risk of refueling workers in the urban service station at the 95th percentile slightly exceeded the maximum acceptable carcinogen risk (1 × 10(-4)), indicating the potential carcinogenic health effects on the population highly exposed to MTBE in this region. The hazard index and carcinogenic risk of MTBE in drinking water were significantly lower than the safe limit of US Environmental Protection Agency, suggesting that drinking water unlikely poses significant health risks to the residents in Nanning.
本研究调查了中国南方南宁市职业场所空气中、环境空气中和饮用水中甲基叔丁基醚(MTBE)的水平,并评估了其对职业工人和公众的潜在健康风险。结果表明,来自 13 个加油站的职业场所空气中 MTBE 浓度明显高于住宅区环境空气中的浓度(p<0.0001),均远低于美国规定的 MTBE 时间加权平均阈限值(TLV-TWA)。家庭水龙头饮用水样本中 MTBE 的检出浓度为 0.04-0.33μg/L,低于美国 20-40μg/L 的饮用水标准。空气中吸入 MTBE 的非致癌风险可能可以忽略不计,因为计算得出的危害商数小于 1。MTBE 的终生癌症风险平均值在可接受的 1×10(-6)至 1×10(-4)范围内,但城市加油站加油工人在第 95 百分位数处的终生癌症风险略高于最大可接受致癌物风险(1×10(-4)),表明该地区高暴露于 MTBE 的人群存在潜在的致癌健康影响。饮用水中 MTBE 的危害指数和致癌风险明显低于美国环保署的安全限值,表明饮用水不太可能对南宁市居民造成重大健康风险。