转移性结直肠平滑肌肉瘤的肝切除术：单中心经验

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience.

作者信息

Faraj Walid, El-Kehdy Jessica, Nounou Ghina El, Deeba Samer, Fakih Hawraa, Jabbour Mark, Haydar Ali, El Naaj Abdallah Abou, Abou-Alfa Ghassan K, O'Reilly Eileen M, Shamseddine Ali, Khalife Mohamad, Mukherji Deborah

机构信息

1 Liver Transplantation and Hepatopancreaticobiliary Surgery, Department of General Surgery, 2 Department of Surgery, 3 Division of Hematology and Oncology, Department of Internal Medicine, 4 Department of Pathology, American University of Beirut Medical Center, Beirut, Lebanon ; 5 Gastrointestinal Oncology Service, Memorial Sloan Kettering Cancer Center, New York, NY, USA ; 6 Department of Medicine, Weill Cornell Medical College, New York, NY, USA.

出版信息

J Gastrointest Oncol. 2015 Oct;6(5):E70-6. doi: 10.3978/j.issn.2078-6891.2015.044.

DOI:10.3978/j.issn.2078-6891.2015.044

PMID:26487954

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4570914/

Abstract

BACKGROUND

Leiomyosarcoma arising in the colorectum is a rare malignancy of the smooth muscles accounting for less than 1% of gastrointestinal tumors. Surgery remains the most accepted modality for the treatment of this entity however management of liver metastases remains controversial.

METHODS & RESULTS: From 1998 to 2009, five patients diagnosed with primary leiomyosarcoma of colorectal origin with metastatic liver disease, underwent liver resections at the American University of Beirut Medical Center. The median overall survival was 47 months (range, 7-135 months).

CONCLUSIONS

Leiomyosarcoma of colorectal origin with liver metastasis is a very rare entity. Long-term survival can be achieved after surgical resection and should be considered for all patients.

摘要

背景

结直肠平滑肌肉瘤是一种罕见的平滑肌恶性肿瘤，占胃肠道肿瘤的比例不到1%。手术仍然是治疗该疾病最常用的方式，然而肝转移的治疗仍存在争议。

方法与结果

1998年至2009年，5例被诊断为原发性结直肠平滑肌肉瘤并伴有肝转移的患者在美国贝鲁特美国大学医学中心接受了肝切除术。中位总生存期为47个月（范围7 - 135个月）。

结论

结直肠起源的平滑肌肉瘤伴肝转移是一种非常罕见的疾病。手术切除后可实现长期生存，所有患者均应考虑手术。

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本文引用的文献

Analysis of integrin alpha7 mutations in prostate cancer, liver cancer, glioblastoma multiforme, and leiomyosarcoma.

J Natl Cancer Inst. 2007 Jun 6;99(11):868-80. doi: 10.1093/jnci/djk199.

Myomatous tumors of the rectum (leiomyomas and myosarcomas).

Surgery. 1950 Oct;28(4):642-50.

Leiomyosarcoma of the colon.

Br J Radiol. 1961 Nov;34:748-50. doi: 10.1259/0007-1285-34-407-748.

Leiomyosarcoma of the colon in an infant.

Am J Roentgenol Radium Ther Nucl Med. 1960 Sep;84:540-5.

LEIOMYOSARCOMA OF THE COLON.

Am J Surg. 1965 Jun;109:816-8. doi: 10.1016/s0002-9610(65)80060-5.

Leiomyosarcoma of the colon.

Am J Roentgenol Radium Ther Nucl Med. 1963 Apr;89:766-70.

Smooth muscle tumors of the stomach.

Int Abstr Surg. 1960 Mar;110:209-26.

Smooth muscle tumors of the gastrointestinal tract.

Am Surg. 1960 Oct;26:666-77.

Smoothmuscle tumors of the alimentary tract; their roentgen manifestations.

Am J Roentgenol Radium Ther Nucl Med. 1955 Aug;74(2):246-55.

Leiomyoma and leiomyosarcoma of the colon.

Ann Surg. 1954 Jan;139(1):67-75. doi: 10.1097/00000658-195401000-00008.

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转移性结直肠平滑肌肉瘤的肝切除术：单中心经验

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience.

作者信息

机构信息

出版信息

J Gastrointest Oncol. 2015 Oct;6(5):E70-6. doi: 10.3978/j.issn.2078-6891.2015.044.

DOI:10.3978/j.issn.2078-6891.2015.044

PMID:26487954

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4570914/

Abstract

BACKGROUND

CONCLUSIONS

Leiomyosarcoma of colorectal origin with liver metastasis is a very rare entity. Long-term survival can be achieved after surgical resection and should be considered for all patients.

摘要

背景

结直肠平滑肌肉瘤是一种罕见的平滑肌恶性肿瘤，占胃肠道肿瘤的比例不到1%。手术仍然是治疗该疾病最常用的方式，然而肝转移的治疗仍存在争议。

方法与结果

结论

结直肠起源的平滑肌肉瘤伴肝转移是一种非常罕见的疾病。手术切除后可实现长期生存，所有患者均应考虑手术。

转移性结直肠平滑肌肉瘤的肝切除术：单中心经验

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience.

作者信息

机构信息

出版信息

BACKGROUND

CONCLUSIONS

背景

方法与结果

结论

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转移性结直肠平滑肌肉瘤的肝切除术：单中心经验

Liver resection for metastatic colorectal leiomyosarcoma: a single center experience.

作者信息

机构信息

出版信息

BACKGROUND

CONCLUSIONS

背景

方法与结果

结论