急性冠状动脉综合征：一例罕见的伴嗜铬细胞瘤和甲状腺髓样癌的多发性内分泌肿瘤综合征病例。

Acute coronary syndrome: a rare case of multiple endocrine neoplasia syndromes with pheochromocytoma and medullary thyroid carcinoma.

作者信息

Maloberti Alessadro, Meani Paolo, Pirola Roberto, Varrenti Marisa, Boniardi Marco, De Biase Anna Maria, Vallerio Paola, Bonacina Edgardo, Mancia Giuseppe, Loli Paola, Giannattasio Cristina

机构信息

1 Health Science Department, Milano-Bicocca University, Milan 20159, Italy ; 2 Cardiology IV, "A. De Gasperis" Department, Ospedale Niguarda Ca' Granda, Milan 20159, Italy ; 3 General Oncologic and Mini-invasive Surgery Department, 4 Anatomy and Histology Department, 5 Endocrine Unit, Niguarda Ca' Granda Hospital, Milan 20159, Italy.

出版信息

Cancer Biol Med. 2015 Sep;12(3):255-8. doi: 10.7497/j.issn.2095-3941.2015.0016.

DOI:10.7497/j.issn.2095-3941.2015.0016

PMID:26487970

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4607818/

Abstract

Pheochromocytoma is a tumor arising from neuroectodermal chromaffin tissues in the adrenal gland or extra-adrenal paraganglia (paragangliomas). The prevalence of the tumor is 0.1%-0.6% in the hypertensive population, of which 10%-20% are malignant. Pheochromocytoma produces, stores, and secretes catecholamines, as well as leads to hypertensive crisis, arrhythmia, angina, and acute myocardial infarction without coronary artery diseases. We report a case of acute coronary syndrome (ACS) with a final diagnosis of multiple endocrine neoplasia with pheochromocytoma and medullary thyroid carcinoma (MTC).

摘要

嗜铬细胞瘤是一种起源于肾上腺或肾上腺外副神经节（副神经节瘤）中神经外胚层嗜铬组织的肿瘤。该肿瘤在高血压人群中的患病率为0.1%-0.6%，其中10%-20%为恶性。嗜铬细胞瘤产生、储存和分泌儿茶酚胺，还会引发高血压危象、心律失常、心绞痛以及无冠状动脉疾病的急性心肌梗死。我们报告一例急性冠状动脉综合征（ACS）病例，最终诊断为多发性内分泌腺瘤病合并嗜铬细胞瘤和甲状腺髓样癌（MTC）。