Hosseini Mostafa, Ghelichkhani Parisa, Baikpour Masoud, Tafakhori Abbas, Asady Hadi, Haji Ghanbari Mohammad Javad, Yousefifard Mahmoud, Safari Saeed
Sina Trauma and Surgery Research Center, Tehran University Medical Sciences, Tehran, Iran. ; Department of Epidemiology and Biostatistics, school of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Department of Intensive Care Nursing, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran.
Emerg (Tehran). 2015 Fall;3(4):127-36.
Ultrasonography is currently being used as one of the diagnostic modalities in various medical emergencies for screening of trauma patients. The diagnostic value of this modality in detection of traumatic chest injuries has been evaluated by several studies but its diagnostic accuracy in diagnosis of pulmonary contusion is a matter of discussion. Therefore, the present study aimed to determine the diagnostic accuracy of ultrasonography and radiography in detection of pulmonary contusion through a systematic review and meta-analysis.
An extended systematic search was performed by two reviewers in databases of Medline, EMBASE, ISI Web of Knowledge, Scopus, Cochrane Library, and ProQuest. They extracted the data and assessed the quality of the studies. After summarization of data into true positive, false positive, true negative, and false negative meta-analysis was carried out via a mixed-effects binary regression model. Further subgroup analysis was performed due to a significant heterogeneity between the studies.
12 studies were included in this meta-analysis (1681 chest trauma patients, 76% male). Pooled sensitivity of ultrasonography in detection of pulmonary contusion was 0.92 (95% CI: 0.81-0.96; I2= 95.81, p<0.001) and its pooled specificity was calculated to be 0.89 (95% CI: 0.85-0.93; I2 = 67.29, p<0.001) while these figures for chest radiography were 0.44 (95% CI: 0.32-0.58; I2= 87.52, p<0.001) and 0.98 (95% CI: 0.88-1.0; I2= 95.22, p<0.001), respectively. Subgroup analysis showed that the sources of heterogeneity between the studies were sampling method, operator, frequency of the transducer, and sample size.
Ultrasonography was found to be a better screening tool in detection of pulmonary contusion. Moreover, an ultrasonography performed by a radiologist / intensivist with 1-5MHz probe has a higher diagnostic value in identifying pulmonary contusions.
超声检查目前被用作各种医疗急症中创伤患者筛查的诊断手段之一。多项研究评估了该手段在检测创伤性胸部损伤中的诊断价值,但其在诊断肺挫伤方面的诊断准确性仍存在争议。因此,本研究旨在通过系统评价和荟萃分析确定超声检查和X线摄影在检测肺挫伤方面的诊断准确性。
两名研究者在Medline、EMBASE、ISI Web of Knowledge、Scopus、Cochrane图书馆和ProQuest数据库中进行了扩展的系统检索。他们提取数据并评估研究质量。在将数据汇总为真阳性、假阳性、真阴性和假阴性后,通过混合效应二元回归模型进行荟萃分析。由于研究之间存在显著异质性,因此进行了进一步的亚组分析。
本荟萃分析纳入了12项研究(1681例胸部创伤患者,76%为男性)。超声检查检测肺挫伤的合并敏感度为0.92(95%CI:0.81 - 0.96;I2 = 95.81,p<0.001),其合并特异度计算为0.89(95%CI:0.85 - 0.93;I2 = 67.29,p<0.001),而胸部X线摄影的相应数字分别为0.44(95%CI:0.32 - 0.58;I2 = 87.52,p<0.001)和0.98(95%CI:0.88 - 1.0;I2 = 95.22,p<0.001)。亚组分析表明,研究之间异质性的来源包括抽样方法、操作者、换能器频率和样本量。
超声检查被发现是检测肺挫伤的更好筛查工具。此外,由放射科医生/重症监护医生使用1 - 5MHz探头进行的超声检查在识别肺挫伤方面具有更高的诊断价值。