快照：抗病毒限制因子。

SnapShot: antiviral restriction factors.

机构信息

Institute of Molecular Virology, Ulm University Medical Center, 89081 Ulm, Germany.

出版信息

Cell. 2015 Oct 22;163(3):774-774.e1. doi: 10.1016/j.cell.2015.10.019.

DOI:10.1016/j.cell.2015.10.019

Abstract

Restriction factors are cellular proteins that inhibit viruses at different steps of their replication cycle and represent an important first line of defense against viral pathogens. This SnapShot provides an overview of cell-intrinsic antiviral factors, describes their properties, and illustrates the striking variety of antiviral mechanisms as well the sophisticated viral countermeasures. To view this SnapShot, open or download the PDF.

摘要

限制因子是细胞蛋白，可在病毒复制周期的不同阶段抑制病毒，是针对病毒病原体的重要第一道防线。本 SnapShot 概述了细胞内抗病毒因子，描述了它们的特性，并说明了抗病毒机制的显著多样性以及复杂的病毒对策。要查看此 SnapShot，请打开或下载 PDF。