支持定量蛋白质组学以鉴定巴西副球孢子菌分离株中潜在毒力调节因子的数据。
Data in support of quantitative proteomics to identify potential virulence regulators in Paracoccidioides brasiliensis isolates.
作者信息
Tashima Alexandre Keiji, Castilho Daniele Gonçalves, Chaves Alison Felipe Alencar, Xander Patricia, Zelanis André, Batista Wagner Luiz
机构信息
Departamento de Bioquímica, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
Departamento de Microbiologia, Imunologia e Parasitologia, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
出版信息
Data Brief. 2015 Sep 9;5:155-60. doi: 10.1016/j.dib.2015.09.001. eCollection 2015 Dec.
Paracoccidioides genus are the etiologic agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic in Latin America. Few virulence factors have been identified in these fungi. This paper describes support data from the quantitative proteomics of Paracoccidioides brasiliensis attenuated and virulent isolates [1]. The protein compositions of two isolates of the Pb18 strain showing distinct infection profiles were quantitatively assessed by stable isotopic dimethyl labeling and proteomic analysis. The mass spectrometry and the analysis dataset have been deposited to the ProteomeXchange Consortium via the PRIDE partner repository with identifier PXD000804.
副球孢子菌属是副球孢子菌病（PCM）的病原体，PCM是一种在拉丁美洲流行的全身性真菌病。在这些真菌中已鉴定出的毒力因子很少。本文描述了来自巴西副球孢子菌减毒株和强毒株定量蛋白质组学的支持数据[1]。通过稳定同位素二甲基标记和蛋白质组学分析对显示出不同感染特征的Pb18菌株的两个分离株的蛋白质组成进行了定量评估。质谱和分析数据集已通过PRIDE合作伙伴库存入蛋白质组交换联盟，标识符为PXD000804。
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