Bochatay L, Elkrief L, Spahr L
Rev Med Suisse. 2015 Sep 2;11(484):1596, 1598-601.
The beneficial effects of the use of albumin, either alone or combines with other treat- ments, have been demonstrated in patients with various complications of cirrhosis. Therefore, albumin should be administred in patients with spontaneous bacterial peritonitis in association with antibiotics, and in association with terlipressin in patients with type 1 hepatorenal syndrome. Albumin use reduces the occurrence of paracentesis-related circulatory dysfunction, in patients with large ascites undergoing paracentesis. So far, the beneficial effect of albumin has not been demonstrated, neither for infections other than spontaneous bacterial peritonitis nor for hepatic encephalopathy. This article provides an overview of the data evaluating the effects of albumin in patients with cirrhosis.
单独使用白蛋白或与其他治疗方法联合使用白蛋白的有益效果,已在患有各种肝硬化并发症的患者中得到证实。因此,对于自发性细菌性腹膜炎患者,白蛋白应与抗生素联合使用;对于1型肝肾综合征患者,白蛋白应与特利加压素联合使用。在进行腹腔穿刺术的大量腹水患者中,使用白蛋白可减少腹腔穿刺术相关循环功能障碍的发生。到目前为止,白蛋白的有益效果尚未在除自发性细菌性腹膜炎以外的其他感染或肝性脑病患者中得到证实。本文概述了评估白蛋白对肝硬化患者疗效的数据。