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使用SYNTAX评分比较冠状动脉风险评分系统以预测冠状动脉疾病的严重程度。

Comparison of coronary risk scoring systems to predict the severity of coronary artery disease using the SYNTAX score.

作者信息

Tolunay Hatice, Kurmus Ozge

机构信息

Clinic of Cardiology, Abdurrahman Yurtaslan Ankara Oncology Education and Research Hospital, Ankara, Turkey.

出版信息

Cardiol J. 2016;23(1):51-6. doi: 10.5603/CJ.a2015.0074. Epub 2015 Oct 27.

Abstract

BACKGROUND

Reliable risk scoring systems that can predict the severity of coronary artery disease (CAD) are necessary to implement effective management strategies in high-risk patients. Atherosclerotic vascular disease and with cardiovascular morbidity and mortality risk are patients who would benefit most from a change in patients at high risk factors. Framingham Risk Score, the Prospective Cardiovascular Münster (PROCAM) score and Systematic Coronary Risk Evaluation (SCORE) risk scores are used for this purpose. The severity of the CAD as detected by coronary angiography can be estimated using the SYNTAX score. In this study, it is aimed to assess the relation between SYNTAX score and the Framingham, PROCAM and SCORE scores in the context of their utility for the determination of the severity of the CAD.

METHODS

A total of 205 patients with documented CAD who underwent coronary angiography due to a diagnosis of stable angina pectoris were included in this study. Coronary risk scores were determined for each patient. The relation between the SYNTAX score and the results of coronary risk scoring systems were analyzed.

RESULTS

A positive relationship between the SYNTAX score, which reflects the severity of the CAD and coronary risk scores was found. However, Framingham and SCORE were superior, i.e., had more predictive value, regarding their ability to predict the SYNTAX score (p = 0.029, 0.033 and 0.002, respectively).

CONCLUSIONS

Examination of the distribution of SYNTAX score across low, intermediate and high-risk groups showed a significantly higher predictive value of SCORE for high-risk patients (p = 0.005).

摘要

背景

可靠的风险评分系统对于在高危患者中实施有效的管理策略、预测冠状动脉疾病(CAD)的严重程度是必要的。动脉粥样硬化性血管疾病以及具有心血管发病和死亡风险的患者是那些因高危因素改变而受益最大的患者。为此使用了弗明汉姆风险评分、前瞻性心血管明斯特(PROCAM)评分和系统性冠状动脉风险评估(SCORE)风险评分。可使用SYNTAX评分来估计冠状动脉造影检测到的CAD严重程度。在本研究中,旨在评估SYNTAX评分与弗明汉姆、PROCAM和SCORE评分在确定CAD严重程度的效用方面的关系。

方法

本研究纳入了总共205例因诊断为稳定型心绞痛而接受冠状动脉造影的确诊CAD患者。为每位患者确定冠状动脉风险评分。分析了SYNTAX评分与冠状动脉风险评分系统结果之间的关系。

结果

发现反映CAD严重程度的SYNTAX评分与冠状动脉风险评分之间存在正相关关系。然而,就预测SYNTAX评分的能力而言,弗明汉姆评分和SCORE评分更优,即具有更高的预测价值(p分别为0.029、0.033和0.002)。

结论

对SYNTAX评分在低、中、高危组中的分布进行检查发现,SCORE评分对高危患者具有显著更高的预测价值(p = 0.005)。

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