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儿童在学校内滥用、误用药物及有自杀性药物使用行为。

Abuse, misuse, and suicidal substance use by children on school property.

作者信息

Vakkalanka J Priyanka, King Joshua D, Holstege Christopher P

机构信息

a Division of Medical Toxicology, Department of Emergency Medicine , University of Virginia School of Medicine , Charlottesville , VA , USA.

b Department of Internal Medicine University of Virginia School of Medicine , Charlottesville , VA , USA.

出版信息

Clin Toxicol (Phila). 2015 Nov;53(9):901-7. doi: 10.3109/15563650.2015.1085998.

Abstract

OBJECTIVE

The purpose of this study was to characterize the epidemiological trends associated with substances used in intentional exposures among children while on school property reported to the U.S. National Poison Data System (NPDS).

MATERIALS AND METHODS

NPDS was queried for intentional (abuse, misuse, suspected suicide, and unknown intentional) exposures reported to occur on school property between calendar years 2004 and 2013. Records were restricted to children 6-18 years of age. Demographic, exposure, and clinical characteristics were assessed.

RESULTS

A total of 56,882 substances were intentionally used on school property by 50,379 children, of which 39.8% were females (n = 20,070), 57.7% were males (n = 29,084), and 2.4% were unknown gender (n = 1,225). The most frequent pharmaceutical exposures reported included sedatives (n = 4,096; 8.1%), analgesics (n = 4,022; 8.0%), and cough and cold preparations (n = 3,529; 7.0%). The majority of exposures were managed on site (n = 21,464; 42.6%), followed by care at a healthcare facility (n = 20,048; 39.7%). Serious outcomes (moderate or major effects and death) accounted for nine percent of all reported exposures. Compared to reference groups, female gender, teenagers 17-18 years, and pharmaceutical substances (Prevalence Ratios = 4.6, 9.4, and 9.9, respectively) were associated with suspected suicides when compared with other intentional exposures.

CONCLUSIONS

Along with other national data about behaviors in the adolescent and teenage population, additional trends in risky behavior may be gleaned by surveillance through poison centers. With over 5,000 annual reports to the poison centers about intentional exposures on school property, school personnel and parents/guardians must be vigilant about the range of pharmaceutical and non-pharmaceutical substances that are used for abuse, misuse, or suicide.

摘要

目的

本研究旨在描述向美国国家中毒数据系统(NPDS)报告的在学校场所内儿童故意接触物质的相关流行病学趋势。

材料与方法

查询NPDS中2004年至2013年期间报告发生在学校场所内的故意(滥用、误用、疑似自杀及不明故意)接触事件。记录限于6至18岁儿童。对人口统计学、接触情况及临床特征进行评估。

结果

50379名儿童在学校场所故意使用了总计56882种物质,其中39.8%为女性(n = 20070),57.7%为男性(n = 29084),2.4%性别不明(n = 1225)。报告的最常见药物接触包括镇静剂(n = 4096;8.1%)、镇痛药(n = 4022;8.0%)以及止咳感冒药(n = 3529;7.0%)。大多数接触事件在现场处理(n = 21464;42.6%),其次是在医疗机构处理(n = 20048;39.7%)。严重后果(中度或重度影响及死亡)占所有报告接触事件的9%。与参照组相比,女性、17 - 18岁青少年以及药物(患病率比值分别为4.6、9.4和9.9)与疑似自杀相关,而与其他故意接触情况相比。

结论

除了关于青少年人群行为的其他国家数据外,通过毒物中心监测可收集到更多危险行为趋势。每年向毒物中心报告的学校场所故意接触事件超过5000起,学校工作人员及家长/监护人必须对用于滥用、误用或自杀的各类药物及非药物物质保持警惕。

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