肥胖糖尿病女性孕期体重增加不足的影响。
The impact of inadequate gestational weight gain in obese diabetic women.
作者信息
Kurnit K C, Overcash R T, Ramos G A, LaCoursiere D Y
机构信息
Department of Reproductive Medicine, University of California San Diego, San Diego, CA, USA.
Division of Maternal-Fetal Medicine, Department of Obsteterics and Gynecology, MedStar Washington Hospital Center, Washington, DC, USA.
出版信息
J Perinatol. 2016 Feb;36(2):86-9. doi: 10.1038/jp.2015.155. Epub 2015 Nov 5.
OBJECTIVE
To determine the effect of inadequate gestational weight gain (GWG) on neonatal birth weight in diabetic obese women.
STUDY DESIGN
Retrospective cohort study of women with an initial body mass index (BMI) ⩾30 kg m(-2) and gestational or type 2 diabetes was conducted. GWG was stratified: inadequate (<11 lbs), adequate (11 to 20 lbs) or excessive (>20 lbs). The primary outcome was birth weight. Secondary outcomes included hypertensive disorders, gestational age at delivery, mode of delivery and Apgar scores.
RESULT
A total of 211 obese diabetic women were identified. Of those, 37% had inadequate GWG, 25% had adequate GWG and 38% had excessive GWG. Women with inadequate GWG had lower mean birth weights (P=0.048), as well as lower rates of cesarean delivery (P=0.017) and lower rates of pregnancy-related hypertensive disorders (P=0.026) compared with those with adequate and excessive GWG.
CONCLUSION
Inadequate GWG was associated lower mean birth weights, lower rates of cesarean delivery and lower rates of pregnancy-related hypertensive disorders.
目的
确定孕期体重增加不足（GWG）对糖尿病肥胖女性新生儿出生体重的影响。
研究设计
对初始体重指数（BMI）⩾30 kg m(-2) 且患有妊娠期糖尿病或2型糖尿病的女性进行回顾性队列研究。GWG被分为：不足（<11磅）、充足（11至20磅）或过多（>20磅）。主要结局是出生体重。次要结局包括高血压疾病、分娩孕周、分娩方式和阿氏评分。
结果
共纳入211名肥胖糖尿病女性。其中，37%的女性GWG不足，25%的女性GWG充足，38%的女性GWG过多。与GWG充足和过多的女性相比，GWG不足的女性平均出生体重较低（P=0.048），剖宫产率较低（P=0.017），妊娠相关高血压疾病发生率较低（P=0.026）。
结论
GWG不足与较低的平均出生体重、较低的剖宫产率和较低的妊娠相关高血压疾病发生率相关。
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