Suppr超能文献

从靶点到治疗:架起自身免疫研究的桥梁以加深对斑秃的理解

From Targets to Treatments: Bridging Autoimmune Research to Advance Understanding of Alopecia Areata.

作者信息

Kranz Dory, Ellison Abby, Frelinger Jeffrey A, Mackay-Wiggan Julian, Norris David A

机构信息

National Alopecia Areata Foundation, San Rafael, California, USA.

Department of Immunobiology, University of Arizona, Tucson, Arizona, USA.

出版信息

J Investig Dermatol Symp Proc. 2015 Nov;17(2):1-5. doi: 10.1038/jidsymp.2015.29.

Abstract

Alopecia areata is a common autoimmune skin disease resulting in the loss of hair on the scalp and elsewhere on the body that affects over 146 million people worldwide at some point in their lives. Founded in 1981, the National Alopecia Areata Foundation (NAAF) is a nonprofit organization that supports research to find a cure or acceptable treatment for alopecia areata, supports those with the disease, and educates the public about alopecia areata. NAAF conducts research summits every 2 years that are central to achieving the goals of a major strategic initiative, the Alopecia Areata Treatment Development Program, which are: to accelerate progress toward a safe, effective, affordable treatment or a cure for alopecia areata. These summits have played a key role in transforming the understanding of alopecia areata from largely inflammatory and dermatological perspectives to a focus on the genetic and immunological factors that are now recognized as driving and active determinants of the disease process.

摘要

斑秃是一种常见的自身免疫性皮肤病,会导致头皮和身体其他部位脱发,全球超过1.46亿人在人生的某个阶段会受到影响。美国国家斑秃基金会(NAAF)成立于1981年,是一个非营利组织,致力于支持寻找斑秃治疗方法或可接受治疗方案的研究,为患者提供支持,并向公众普及斑秃知识。NAAF每两年举办一次研究峰会,这对于实现一项重大战略计划——斑秃治疗开发项目的目标至关重要,该项目的目标是:加快迈向安全、有效、可负担的斑秃治疗方法或治愈方案的进程。这些峰会在将对斑秃的理解从主要的炎症和皮肤病学角度,转变为关注现在被认为是驱动和决定疾病进程的遗传和免疫因素方面发挥了关键作用。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验