Demarzo Marcelo M P, Montero-Marin Jesús, Cuijpers Pim, Zabaleta-del-Olmo Edurne, Mahtani Kamal R, Vellinga Akke, Vicens Caterina, López-del-Hoyo Yolanda, García-Campayo Javier
Federal University of Sao Paulo (UNIFESP), "Mente Aberta" - Brazilian Center for Mindfulness and Health Promotion, Department of Preventive Medicine, Sao Paulo, Brazil.
Faculty of Health Sciences and Sports, University of Zaragoza, Huesca, Spain.
Ann Fam Med. 2015 Nov;13(6):573-82. doi: 10.1370/afm.1863.
Positive effects have been reported after mindfulness-based interventions (MBIs) in diverse clinical and nonclinical populations. Primary care is a key health care setting for addressing common chronic conditions, and an effective MBI designed for this setting could benefit countless people worldwide. Meta-analyses of MBIs have become popular, but little is known about their efficacy in primary care. Our aim was to investigate the application and efficacy of MBIs that address primary care patients.
We performed a meta-analytic review of randomized controlled trials addressing the effect of MBIs in adult patients recruited from primary care settings. The PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and Cochrane guidelines were followed. Effect sizes were calculated with the Hedges g in random effects models.
The meta-analyses were based on 6 trials having a total of 553 patients. The overall effect size of MBI compared with a control condition for improving general health was moderate (g = 0.48; P = .002), with moderate heterogeneity (I(2) = 59; P <.05). We found no indication of publication bias in the overall estimates. MBIs were efficacious for improving mental health (g = 0.56; P = .007), with a high heterogeneity (I(2) = 78; P <.01), and for improving quality of life (g = 0.29; P = .002), with a low heterogeneity (I(2) = 0; P >.05).
Although the number of randomized controlled trials applying MBIs in primary care is still limited, our results suggest that these interventions are promising for the mental health and quality of life of primary care patients. We discuss innovative approaches for implementing MBIs, such as complex intervention and stepped care.
基于正念的干预措施(MBIs)已在不同临床和非临床人群中显示出积极效果。初级保健是应对常见慢性病的关键医疗保健环境,为此环境设计的有效MBI可为全球无数人带来益处。对MBIs的荟萃分析已很常见,但对其在初级保健中的疗效知之甚少。我们的目的是研究针对初级保健患者的MBIs的应用及疗效。
我们对从初级保健机构招募的成年患者中探讨MBIs效果的随机对照试验进行了荟萃分析综述。遵循PRISMA(系统评价和荟萃分析的首选报告项目)和Cochrane指南。在随机效应模型中用Hedges g计算效应量。
荟萃分析基于6项试验,共有553名患者。与对照条件相比,MBI改善总体健康的总体效应量为中等(g = 0.48;P = 0.002),异质性中等(I(2)=59;P < 0.05)。我们在总体估计中未发现发表偏倚迹象。MBIs对改善心理健康有效(g = 0.56;P = 0.007),异质性高(I(2)=78;P < 0.01),对改善生活质量也有效(g = 0.29;P = 0.002),异质性低(I(2)=0;P > 0.05)。
尽管在初级保健中应用MBIs的随机对照试验数量仍然有限,但我们的结果表明,这些干预措施对初级保健患者的心理健康和生活质量具有前景。我们讨论了实施MBIs的创新方法,如复杂干预和阶梯式护理。