Fiedler A, Sauter-Louis C, Maierl J
Andrea Fiedler, Heerstrasse 3, 81247 Munich, Germany, Email:
Tierarztl Prax Ausg G Grosstiere Nutztiere. 2015;43(6):350-8. doi: 10.15653/TPG-140751. Epub 2015 Nov 10.
The use of antibiotics is a proven approach for local and systemic treatment of digital dermatitis (DD). Even if they are administered only locally and at low dosage, their use should be restricted to an absolute minimum. The efficacy of a commercial polyurethane wound dressing in treating acute digital dermatitis was compared with topical treatment using a commercially available tetracycline spray and a salicylic acid paste.
A total of 105 cows in a dairy farm (with about 160 dairy cows) were included in the study, with 101 cows needing topical treatment for digital dermatitis on one or both hind feet. All animals underwent hoof trimming prior to the treatment. Affected feet (n = 152) were randomly assigned to one of three comparable treatment groups. Topical treatment was administered to all visible digital dermatitis lesions. Animals in the positive control groups were given a topical treatment of tetracycline (53 DD lesions in 49 cows) or salicylic acid (53 DD lesions in 50 cows) formulations, whose therapeutic effects were scientifically verified. Spray was applied once, at a usual dosage and without any bandage. Salicylic acid paste was fixed in place with a bandage for 5 days. In the test group (46 DD lesions in 45 cows), a polyurethane bandage was left in place for 10 days. Whereas, 47 feet (from 38 cows) without lesions or with lesions showing no pain were designated as group 0. Each lesion was evaluated at day 0 during trimming, and on day 10 and 36. The lesions were scored based on severity and size.
All groups showed a statistically significant improvement in the clinical appearance of the lesions at day 10. There were no significant differences in the findings between the second and the third evaluation (day 10 and day 36) either within a group or between the groups.
The use of an alternative treatment regimen like a polyurethane wound dressing shows good clinical healing, it is as effective as the conventional methods, and unlike the conventional methods, does not require a latency period.
使用抗生素是治疗指皮炎(DD)的局部和全身的一种行之有效的方法。即使仅局部低剂量使用,其使用也应限制在绝对最小值。将一种商用聚氨酯伤口敷料治疗急性指皮炎的疗效与使用市售四环素喷雾剂和水杨酸糊剂的局部治疗进行比较。
一个奶牛场(约160头奶牛)的105头奶牛纳入研究,其中101头奶牛一只或两只后蹄需要对指皮炎进行局部治疗。所有动物在治疗前均进行蹄部修剪。将受影响的蹄子(n = 152)随机分配到三个可比治疗组之一。对所有可见的指皮炎病变进行局部治疗。阳性对照组的动物接受四环素(49头奶牛的53处DD病变)或水杨酸(50头奶牛的53处DD病变)制剂的局部治疗,其治疗效果经过科学验证。喷雾剂以常规剂量使用一次,不使用任何绷带。水杨酸糊剂用绷带固定5天。试验组(45头奶牛的46处DD病变)使用聚氨酯绷带10天。而47只蹄子(来自38头奶牛)无病变或病变无痛,被指定为0组。在修剪时的第0天、第10天和第36天对每个病变进行评估。根据严重程度和大小对病变进行评分。
所有组在第10天时病变的临床表现均有统计学显著改善。在第二次和第三次评估(第